China Factory Direct
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| CAS number | 64700-65-8 |
| Product name | (-)-D-PYROGLUTAMIC ACID METHYL ESTER |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty GradeCosmetic GradeFood Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of active pharmaceutical ingredients (APIs) | Used as an intermediate in multistep synthesis |
| Pesticides | Production of insecticides or herbicides | Applied in substitution or condensation reactions |
| Fragrances | Synthesis of fragrance compounds | Used as a raw material in transesterification reactions |
| Dyes & Pigments | Production of dyes or pigments | Applied in polycondensation or other organic synthesis reactions |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 210 nm, based on peak area comparison against reference standard. |
| Enantiomeric Excess (ee) | Chiral HPLC | Measures enantiomeric purity by separation on a chiral stationary phase and UV detection, calculating ee from peak area ratio of (R) and (S) enantiomers. |
| Residual Solvents | GC-FID | Detects and quantifies volatile organic solvents (e.g., methanol, ethyl acetate) using gas chromatography with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration | Determines water by coulometric or volumetric titration with iodine-based reagent, where water reacts stoichiometrically to generate endpoint current or volume change. |
| Heavy Metals | ICP-MS | Quantifies trace metals (e.g., Pb, Cd, Ni) after acid digestion using inductively coupled plasma mass spectrometry for multi-element detection at sub-ppq levels. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after anion exchange column separation. |
| Related Substances | HPLC-UV | Identifies and quantifies structurally related impurities (e.g., hydrolysis products, isomers) via gradient HPLC-UV with system suitability and threshold reporting. |
| Optical Rotation | [alpha]D Measurement | Measures specific rotation using sodium D-line light in a polarimeter to confirm chiral integrity and batch-to-batch consistency. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using controlled heating and visual observation of meniscus collapse. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic ash content by ignition at 700-800 C followed by precise weighing of residual residue. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determines acidity/basicity of a saturated aqueous suspension using calibrated pH electrode and meter. |
| Particle Size Distribution | Laser Diffraction | Analyzes size distribution of solid particles in suspension using angular scattering pattern of laser light and Mie theory calculation. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow sticky liquid |
| Purity | >=98.0% (GC-MS) |
| Optical Rotation | -8.6 ± 0.5° (c=1, in CHCl3) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.