China Factory Direct
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| CAS number | 647829-43-4 |
| Product name | Bis(4-iodophenyl) sulfoxide |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
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| Organic Synthesis | Used as an intermediate in the synthesis of complex organic molecules, particularly in pharmaceuticals and functional materials | Introduces a phenyl iodide moiety via coupling or nucleophilic substitution reactions to construct carbon–sulfur or carbon–carbon bonds |
| Pharmaceutical R&D | Used to synthesize biologically active compounds, such as anticancer or antiviral drug candidates | Serves as a key intermediate in multistep syntheses, leveraging its iodine atom for subsequent functionalization |
| Materials Science | Used in the preparation of functional polymers or optoelectronic materials, such as organic semiconductors | Participates in polymerization via metal-catalyzed coupling reactions, including Suzuki and Stille couplings |
| Fine Chemicals | Used as a high-value chemical in specific chemical transformations | Undergoes catalytic transformation under low-temperature or inert-atmosphere conditions to maintain both stability and reactivity of the phenyl iodide moiety |
| Detection Item | Common Detection Method | Method Overview |
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| Purity (Main Component Content) | HPLC (High-Performance Liquid Chromatography) | Using a C18 reverse-phase chromatographic column, with acetonitrile-water (or buffer salt) as the mobile phase, and a UV detector (typically at 254 nm or 280 nm). Quantification of the main component is performed using external standard or internal standard methods to assess product purity. This method can also detect related impurities simultaneously. |
| Impurity Profile (Organic Impurities) | HPLC-MS (Liquid Chromatography-Mass Spectrometry Coupling) | Based on HPLC separation, mass spectrometry detectors (ESI or APCI mode) are used for structural identification of known or unknown impurities, such as unreacted raw materials (4-iodobenzenethiol), oxidation products (bis(4-iodophenyl) sulfone), deiodination products, etc. |
| Iodine Content | Ion Chromatography (IC) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Organic iodine is converted into inorganic iodide ions (I⁻) through alkaline digestion, then separated and detected by ion chromatography. Alternatively, ICP-MS can be used to directly measure total iodine content to verify the stoichiometric ratio of iodine atoms in the molecule. |
| Water Content | Karl Fischer Titration | The water content is determined quantitatively through a reaction between iodine, sulfur dioxide, pyridine, and methanol. Electrochemical or volumetric methods are used to measure trace water content, ensuring compliance with requirements for pharmaceutical or high-purity materials (typically ≤ 0.5%). |
| Melting Point | Melting Point Determination Instrument (Capillary Method or Automatic Melting Point Apparatus) | The melting temperature range of the sample is measured and compared with literature values (approximately 135–140 °C) to preliminarily assess the purity and crystallinity consistency of the product. |
| Appearance and Color | Visual Inspection + Colorimetric Measurement (e.g., Hazen Color) | Observe the solid form (white to off-white crystalline powder) and ensure there are no visible foreign substances. Use a colorimeter to measure the yellow index or Hazen value to evaluate the color quality of the product. |
| Solvent Residue | Gas Chromatography (GC) | Use headspace injection or direct injection GC-FID to detect residual organic solvents (such as DMF, ethanol, ethyl acetate, etc.) from the production process, in compliance with ICH Q3C standards. |
| Particle Size Distribution (if applicable) | Laser Particle Size Analyzer | For formulations requiring control of powder properties, measure the particle size distribution to ensure uniformity and process reproducibility. |
| Stability (Accelerated Testing) | HPLC/UV Monitoring under Accelerated Conditions | Place the sample under elevated temperature (40°C), high humidity (75% RH), or light exposure conditions, and periodically take samples for HPLC analysis to monitor degradation product formation and evaluate chemical stability. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 198–202°C |
| Identification (NMR) | Conforms to reference spectrum |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.