D-Aspartic acid 4-tert-butyl ester Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 64960-75-4 |
| Product name | D-Aspartic acid 4-tert-butyl ester |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for D-Aspartic acid 4-tert-butyl ester
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk D-Aspartic acid 4-tert-butyl ester Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of D-Aspartic acid 4-tert-butyl ester
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Peptide Drug Synthesis | Serves as a D-amino acid building block in peptide synthesis to incorporate D-aspartic acid residues, thereby enhancing enzymatic stability of peptide drugs. |
| Pharmaceutical Chemicals | Protecting Group Application | Employs the tert-butyl ester to protect the side-chain carboxyl group of aspartic acid, preventing side-chain reactions during solid-phase or solution-phase peptide synthesis and enabling cleavage under acidic conditions. |
| Biochemistry | Peptide Structure and Function Studies | Used to synthesize model peptides containing D-amino acids for investigating the effects of D-amino acids on peptide secondary structure and biological activity. |
| Pharmaceutical Chemicals | Pharmaceutical Intermediate | Serves as a raw material for synthesizing specific chiral pharmaceuticals or bioactive molecules. |
Manufacturing Quality Control of D-Aspartic acid 4-tert-butyl ester
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 200-220 nm, comparing peak area against a certified reference standard. |
| Chiral Purity | Chiral HPLC | Enantiomeric excess measured using a chiral stationary phase to separate D- and L-isomers, with UV detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to quantify water via stoichiometric redox reaction. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., THF, toluene, methanol). |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma mass spectrometry. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride anions using suppressed conductivity detection after eluent generation. |
| Sulfated Ash | Gravimetric Analysis | Incineration at 700-800 C followed by weighing of non-volatile inorganic residue. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to confirm chiral integrity and concentration. |
| pH (1% w/v aqueous solution) | pH Meter | Potentiometric measurement of hydrogen ion activity in a standardized aqueous solution. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., hydrolysis products, diastereomers) using gradient HPLC. |
| Residual tert-Butyl Alcohol | GC-FID | Direct injection GC-FID analysis targeting residual t-butanol from esterification step. |
| Microbial Contamination | Membrane Filtration | Quantitative enumeration of aerobic microorganisms per USP <61> using filtration, incubation, and colony counting. |
Technical Specifications of D-Aspartic acid 4-tert-butyl ester
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | +8.5 to +9.5 deg (c=1, in 1M HCl) |
| Melting Point | 142 to 146 °C |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of D-Aspartic acid 4-tert-butyl ester
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of D-Aspartic acid 4-tert-butyl ester
Safety Information of D-Aspartic acid 4-tert-butyl ester
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of D-Aspartic acid 4-tert-butyl ester
Industrial D-Aspartic acid 4-tert-butyl ester Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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