2,3,5,6-Tetrafluoro-4-hydroxy-benzoic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 652-34-6 |
| Product name | 2,3,5,6-Tetrafluoro-4-hydroxy-benzoic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2,3,5,6-Tetrafluoro-4-hydroxy-benzoic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2,3,5,6-Tetrafluoro-4-hydroxy-benzoic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2,3,5,6-Tetrafluoro-4-hydroxy-benzoic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of antiviral drugs and antibiotic intermediates | Used as a key intermediate for constructing benzoic acid derivatives, participating in amidation and esterification reactions via its carboxylic acid functional group |
| Agrochemicals | Preparation of active ingredients for fluorinated fungicides and herbicides | Applied as a fluorinated aromatic acid unit in condensation reactions to introduce fluorophenyl structures and enhance biological activity |
| Materials Science | Synthesis of high-performance fluorinated polymers and liquid crystal materials | Employed as a monomer in condensation polymerization or copolymerization reactions, leveraging its strong polarity and thermal stability to improve material performance |
| Chemical Reagents | Fluorinated aromatic acid reagent for organic synthesis | Used as a standard reagent in coupling reactions (e.g., Suzuki, Buchwald–Hartwig) to introduce fluorophenyl groups |
Manufacturing Quality Control of 2,3,5,6-Tetrafluoro-4-hydroxy-benzoic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 220-254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and threshold limits per ICH Q3B. |
| Residual Solvents | GC-FID | Detection and quantification of volatile organic solvents (e.g., acetone, methanol, ethyl acetate) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content via stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (Pb, Cd, As, Hg, Cr) after acid digestion, using inductively coupled plasma mass spectrometry for sub-ppb sensitivity. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using suppressed conductivity detection after aqueous extraction. |
| Sulfated Ash | Gravimetric Analysis | Residue weight measurement after high-temperature incineration (700-800 C) of sample with sulfuric acid pretreatment. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed as solid-to-liquid phase change using calibrated capillary method per USP <741>. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles under controlled white light and against standard references. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a defined suspension (e.g., 1% w/v in water) using calibrated electrode after equilibration. |
| Particle Size Distribution | Laser Diffraction | Analysis of size distribution in dispersed powder sample using Mie scattering theory and validated wet/dry dispersion protocol. |
| Residual Fluoride | Ion-Selective Electrode (ISE) | Potentiometric measurement of free fluoride ion concentration after alkaline fusion and pH adjustment, using fluoride-specific membrane electrode. |
Technical Specifications of 2,3,5,6-Tetrafluoro-4-hydroxy-benzoic acid
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 178–182 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2,3,5,6-Tetrafluoro-4-hydroxy-benzoic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2,3,5,6-Tetrafluoro-4-hydroxy-benzoic acid
Safety Information of 2,3,5,6-Tetrafluoro-4-hydroxy-benzoic acid
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 2,3,5,6-Tetrafluoro-4-hydroxy-benzoic acid
Industrial 2,3,5,6-Tetrafluoro-4-hydroxy-benzoic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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