2,2-Difluorobenzodioxole-5-carboxaldehyde Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 656-42-8 |
| Product name | 2,2-Difluorobenzodioxole-5-carboxaldehyde |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2,2-Difluorobenzodioxole-5-carboxaldehyde
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2,2-Difluorobenzodioxole-5-carboxaldehyde Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2,2-Difluorobenzodioxole-5-carboxaldehyde
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key chiral intermediate for the synthesis of the antidiabetic drug sitagliptin | Prepared via asymmetric hydrogenation or enzymatic reduction of (S)-2,2-difluoro-1,3-benzodioxol-5-ylmethanol, followed by multistep functionalization to introduce the triazole moiety |
| Agrochemical R&D | Fluorinated heterocyclic building block for designing novel insecticides and fungicides | Participates in cross-coupling reactions—including Suzuki and Heck couplings—to construct C–C bonds and extend bioactive side chains |
| Organic Synthesis | Fluorinated benzodioxole-based ligand or precursor for functional materials | Converted into fluorescent dyes, liquid crystal monomers, or metal–organic framework (MOF) linkers via Wittig reaction, Grignard addition, or oxidative/reductive modification |
Manufacturing Quality Control of 2,2-Difluorobenzodioxole-5-carboxaldehyde
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, calibrated against certified reference standard. |
| Related Substances | HPLC-DAD | Separation and identification of impurities by HPLC coupled with diode array detection; peak area comparison against main component. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common organic solvents based on retention time and calibration curves. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water via stoichiometric reaction. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and others after acid digestion, based on atomic emission intensity at characteristic wavelengths. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column and suppressed conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Incineration at 700-800 C followed by weighing of non-volatile residue after sulfuric acid treatment. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed as solid-to-liquid phase change using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against defined standards under controlled lighting conditions. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral centers in solution at specified concentration and wavelength. |
| pH of Aqueous Suspension | pH Meter | Electrochemical measurement of hydrogen ion activity in a saturated aqueous suspension prepared under standardized conditions. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity patterns to calculate size distribution of dry or dispersed particles. |
Technical Specifications of 2,2-Difluorobenzodioxole-5-carboxaldehyde
| Test Item | Specification |
|---|---|
| Appearance | Yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Melting Point | 42–46°C |
| Odor | Characteristic |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2,2-Difluorobenzodioxole-5-carboxaldehyde
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2,2-Difluorobenzodioxole-5-carboxaldehyde
Safety Information of 2,2-Difluorobenzodioxole-5-carboxaldehyde
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2,2-Difluorobenzodioxole-5-carboxaldehyde
Industrial 2,2-Difluorobenzodioxole-5-carboxaldehyde Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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