N-Cbz-D-glutamic acid alpha-benzyl ester Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 65706-99-2 |
| Product name | N-Cbz-D-glutamic acid alpha-benzyl ester |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for N-Cbz-D-glutamic acid alpha-benzyl ester
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk N-Cbz-D-glutamic acid alpha-benzyl ester Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of N-Cbz-D-glutamic acid alpha-benzyl ester
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in peptide drug synthesis | Used as a protecting group in solid-phase or solution-phase peptide synthesis, particularly for peptides containing glutamic acid side chains |
| Research | Biochemical reagent | Applied in laboratory-scale peptide preparation, modification, and structural studies as an amino acid derivative |
| Biochemistry | Amino acid protection | Protects the α-amino and γ-carboxyl groups of glutamic acid via benzyloxycarbonyl (Cbz) and benzyl ester (OBzl) groups in organic synthesis |
Manufacturing Quality Control of N-Cbz-D-glutamic acid alpha-benzyl ester
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by comparison of peak area against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-UV | Separation and detection of structurally related impurities (e.g., hydrolysis products, isomers) using gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents (e.g., methanol, toluene, DMF) based on retention time and flame ionization response. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine generated in situ to react stoichiometrically with water in the sample. |
| Optical Rotation | [alpha]D Measurement | Determination of specific optical rotation using a polarimeter at specified temperature and wavelength (e.g., 20 deg C, sodium D line). |
| Heavy Metals | ICP-OES | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion and plasma excitation emission spectroscopy. |
| Chloride Content | Ion Chromatography | Separation and conductivity-based detection of chloride ions after aqueous extraction and anion exchange chromatography. |
| Residue on Ignition | Gravimetric Analysis | Measurement of inorganic ash content after high-temperature incineration and weighing of residual residue. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid-to-liquid phase transition occurs under controlled heating. |
| pH of Solution | Potentiometric pH Measurement | Measurement of hydrogen ion activity in a defined aqueous suspension or solution using calibrated glass electrode. |
| Particle Size Distribution | Laser Diffraction | Analysis of particle size distribution based on angular scattering pattern of laser light passing through a dispersed sample. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic microorganisms and detection of specified pathogens via filtration, culture, and colony counting. |
Technical Specifications of N-Cbz-D-glutamic acid alpha-benzyl ester
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | +22.0 to +25.0 deg (c=1, in DMF) |
| Melting Point | 118 to 122 °C |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of N-Cbz-D-glutamic acid alpha-benzyl ester
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of N-Cbz-D-glutamic acid alpha-benzyl ester
Safety Information of N-Cbz-D-glutamic acid alpha-benzyl ester
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of N-Cbz-D-glutamic acid alpha-benzyl ester
Industrial N-Cbz-D-glutamic acid alpha-benzyl ester Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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