China Factory Direct
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| CAS number | 65872-41-5 |
| Product name | 2-(2-Aminothiazole-4-yl)-2-methoxyiminoacetic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Synthesis of antibiotics | Used as an intermediate in the synthesis of cephalosporin antibiotics |
| Pesticide Industry | Insecticide ingredient | Applied in the synthesis of highly effective, low-toxicity organophosphorus insecticides |
| Chemical Industry | Organic synthesis intermediate | Applied in the preparation of other organic compounds containing oxime acid structures |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Assay | High-Performance Liquid Chromatography (HPLC) | Utilizes a reversed-phase C18 column with a mobile phase of phosphate buffer-acetonitrile or methanol, detected by a UV detector (approximately 254 nm). Quantification is performed using the external standard method. This method offers high specificity and good reproducibility, suitable for quantifying the main component. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Using the same HPLC system, gradient elution separates ampthox acid and its degradation impurities (e.g., deacetylated products, isomers, etc.). The peak areas of individual impurities are calculated to control the total impurity level and limits for individual impurities. |
| Residual Solvents | Gas Chromatography (GC) | According to ICH guidelines, detects organic solvents potentially residual from the manufacturing process (e.g., methanol, acetone, ethanol, dichloromethane). A capillary column and FID detector are used with headspace sampling to ensure solvent residues comply with pharmacopoeial standards. |
| Water Content | Karl Fischer Titration | Either volumetric or coulometric methods are employed to precisely determine water content in the sample, controlling it within an acceptable range (e.g., ≤1.0%) to prevent hygroscopicity or instability. |
| Polymorph Analysis | X-ray Powder Diffraction (XRD) | Used to identify different polymorphic forms and ensure batch-to-batch consistency. Different polymorphs may affect solubility and stability, making this a critical quality attribute. |
| Particle Size Distribution | Laser Diffraction Particle Size Analysis | Determines particle size distribution based on laser scattering principles to control the physical properties of the active pharmaceutical ingredient, influencing uniformity and dissolution behavior in formulations. |
| Optical Rotation | Polarimeter Method | Leverages the chiral center of ampthox acid to measure its specific optical rotation, aiding in identification and auxiliary purity assessment. |
| pH Value | pH Meter Method | The sample is dissolved in water at a specified concentration (e.g., 1% w/v), and the pH is measured using a calibrated pH meter to control acidity/basicity for stability assurance. |
| Heavy Metals | Thioacetamide Method (Pharmacopoeial Method) or ICP-MS | Classic pharmacopoeial colorimetric method or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) is used to determine residues of heavy metals such as lead, cadmium, and mercury, ensuring compliance with safety requirements. |
| Microbiological Limits | Microbiological Limit Test | Performs assays for total aerobic microbial count, mold, and yeast according to the Chinese Pharmacopoeia or international pharmacopoeias, along with tests for specified pathogens (e.g., Escherichia coli, Salmonella), ensuring compliance with microbial control requirements. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 128-132°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.