2-Bromo-3,5-difluoropyridine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 660425-16-1 |
| Product name | 2-Bromo-3,5-difluoropyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Bromo-3,5-difluoropyridine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Bromo-3,5-difluoropyridine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Bromo-3,5-difluoropyridine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate for synthesizing active pharmaceutical ingredients (APIs), including antitumor agents and kinase inhibitors | Acts as an aryl halide in coupling reactions (e.g., Suzuki, Heck) to construct C–C bonds, enabling functionalization of substituents on the pyridine ring |
| Agrochemicals | Structural building block for synthesizing novel fluorinated insecticides and fungicides | Introduced into heterocyclic scaffolds via nucleophilic substitution or metal-catalyzed reactions to enhance lipophilicity and biological activity |
| Materials Science | Functionalized intermediate for organic light-emitting diodes (OLEDs) and electron-transport materials | Converted selectively at the bromine site (e.g., via lithiation–boronation) to prepare fluorinated π-conjugated small molecules for tuning HOMO/LUMO energy levels |
Manufacturing Quality Control of 2-Bromo-3,5-difluoropyridine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detector | Quantifies main component by retention time and peak area relative to calibrated standard. |
| Related Substances | High Performance Liquid Chromatography (HPLC) with UV detection | Separates and quantifies impurities based on retention time and UV absorbance at specified wavelength. |
| Residual Solvents | Gas Chromatography (GC) with Headspace sampler | Detects and quantifies volatile organic solvents using equilibrium vapor phase analysis. |
| Water Content | Karl Fischer Titration | Measures water via stoichiometric reaction between iodine, sulfur dioxide, and water in pyridine/methanol medium. |
| Heavy Metals | Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES) | Quantifies elemental metal impurities by atomic emission intensity after plasma atomization. |
| Chloride Impurity | Ion Chromatography (IC) | Separates and detects chloride ions based on anion exchange and conductivity detection. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature ashing and weighing. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using controlled heating and visual observation. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity against standard reference under controlled lighting. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light caused by chiral compounds in solution. |
| pH of Aqueous Solution | pH Meter Measurement | Determines hydrogen ion activity in a saturated aqueous suspension using calibrated electrode. |
| Bulk Density | Graduated Cylinder Method | Calculates mass per unit volume of freely settled powder in standardized cylinder. |
Technical Specifications of 2-Bromo-3,5-difluoropyridine
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow liquid |
| Purity | >=98.0% (GC) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Melting Point | -15 to -10 °C |
| Refractive Index (n20/D) | 1.515–1.525 |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Bromo-3,5-difluoropyridine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Bromo-3,5-difluoropyridine
Packaging of 2-Bromo-3,5-difluoropyridine
Industrial 2-Bromo-3,5-difluoropyridine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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