China Factory Direct
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| CAS number | 660867-80-1 |
| Product name | 2-METHYLPYRIDINE-4-BORONIC ACID PINACOL ESTER |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
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| Pharmaceutical R&D | Boronic ester reagent for Suzuki-Miyaura cross-coupling to synthesize pyridine-containing active pharmaceutical ingredient (API) intermediates | Undergoes cross-coupling with aryl/heteroaryl halides (bromides, chlorides) in the presence of palladium catalysts (e.g., Pd(PPh₃)₄, Pd(dppf)Cl₂) to form C–C bonds; typically conducted under basic conditions (Na₂CO₃, K₃PO₄, or CsF) in inert solvents (1,4-dioxane, DMF, THF) |
| Agrochemical R&D | Building block for 4-substituted-2-methylpyridine motifs in novel insecticides and fungicides | Participates in Suzuki coupling to introduce functionalized aryl fragments, enhancing binding affinity and selectivity toward target enzymes (e.g., nicotinic acetylcholine receptor) |
| Materials Science | Building block for electron-transport or host materials in organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs) | Suzuki coupling incorporates 2-methylpyridin-4-yl pinacol boronate into conjugated polymer or small-molecule backbones to tune HOMO/LUMO energy levels and charge-carrier mobility |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies impurities (e.g., residual starting materials, by-products) via gradient HPLC with UV detection and relative response factors. |
| Residual Solvents | GC-FID | Separates and quantifies volatile organic solvents (e.g., THF, toluene, methanol) using capillary GC with flame ionization detection against calibration standards. |
| Water Content | Karl Fischer Titration | Determines water by coulometric or volumetric titration where iodine reacts stoichiometrically with water in a controlled anhydrous medium. |
| Heavy Metals (as Pb) | ICP-OES | Measures total elemental metal impurities (Pb, Cd, Ni, etc.) after acid digestion by optical emission spectroscopy at element-specific wavelengths. |
| Chloride Content | Ion Chromatography | Quantifies chloride ions using suppressed conductivity detection after separation on an anion-exchange column with carbonate eluent. |
| Residual Boron | ICP-OES | Quantifies total boron content after microwave-assisted acid digestion using boron-specific emission line at 249.773 nm. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid, indicating purity and identity based on crystalline phase behavior. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of visible particulates or discoloration against defined acceptance criteria under controlled lighting. |
| Loss on Drying | Gravimetric Analysis | Measures weight loss after drying under specified vacuum/temperature conditions, reflecting volatile and moisture content. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light to confirm chiral integrity and detect racemization or enantiomeric impurities. |
| Particle Size Distribution | Laser Diffraction | Determines size distribution of solid particles in suspension using Mie scattering theory and intensity pattern analysis of diffracted laser light. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78–82°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.