Sodium L-ascorbyl-2-phosphate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 66170-10-3 |
| Product name | Sodium L-ascorbyl-2-phosphate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeCosmetic GradeFood Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Sodium L-ascorbyl-2-phosphate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Sodium L-ascorbyl-2-phosphate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Sodium L-ascorbyl-2-phosphate
| Industry | Application | Process |
|---|---|---|
| Food Industry | Antioxidant | Added to food products to prevent oxidative degradation |
| Cosmetics Industry | Skin-lightening agent | Incorporated into skincare formulations to enhance absorption via permeation technology |
| Pharmaceutical Industry | Vitamin supplement | Formulated as a stable ascorbic acid derivative in pharmaceutical preparations |
| Life Sciences Research | Research reagent | Used in cell culture and biochemical reactions to protect labile compounds |
Manufacturing Quality Control of Sodium L-ascorbyl-2-phosphate
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Assay (Purity of L-Ascorbic Acid-2-Phosphate Trisodium Salt) | High-Performance Liquid Chromatography (HPLC) | Uses a C18 reversed-phase column with a mobile phase of phosphate buffer-methanol or acetonitrile, and detection by UV detector at 245–265 nm. The content of the main component is quantified by comparing retention time and peak area with a reference standard. This method effectively separates degradation products such as dehydroascorbic acid and ascorbic acid. |
| Phosphate Content Determination | Molybdenum Blue Spectrophotometry | After acid digestion of the sample, phosphate reacts with ammonium molybdate under acidic conditions to form phosphomolybdic heteropoly acid, which is then reduced to a blue complex by a reducing agent (e.g., ascorbic acid or stannous chloride). Absorbance is measured at 700–880 nm, and phosphate content is calculated using a standard curve to verify whether the molar ratio of phosphorus matches the theoretical value (C₆H₆O₉PNa₃). |
| Moisture Content | Karl Fischer Titration | Bases on the quantitative reaction of iodine and sulfur dioxide with water in the presence of pyridine and methanol. Moisture content, including free water and crystalline water, is determined by potentiometric or endpoint indication methods, ensuring compliance with pharmacopoeial or enterprise standards (typically ≤5%). |
| pH Value | Glass Electrode Method (pH Meter) | A 1% (w/v) aqueous solution is prepared and the pH is measured at 25°C using a calibrated pH meter. Ensures the pH falls within the specified range (typically 7.0–8.5), reflecting the acidity/basicity and stability of the product. |
| Heavy Metals Test | Atomic Absorption Spectroscopy (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | After wet digestion of the sample, levels of heavy metals such as lead (Pb), cadmium (Cd), arsenic (As), and mercury (Hg) are determined, ensuring compliance with limits set by the Chinese Pharmacopoeia or ICH Q3D guidelines (e.g., Pb ≤ 10 ppm). |
| Chloride and Sulfate Impurities | Ion Chromatography (IC) or Turbidimetry | Chloride and sulfate ions are separated and detected by ion chromatography, or quantified by turbidimetry after precipitation with silver nitrate (for chlorides) or barium chloride (for sulfates). Controls inorganic impurity levels to ensure product purity. |
| Solubility and Solution Clarity | Visual Turbidity Comparison or UV-Visible Spectrophotometry | The sample is dissolved to a specified concentration in water; transmittance is measured in the visible range (e.g., 400–700 nm), or clarity is assessed visually to ensure no visible suspended particles or turbidity, reflecting solubility performance and residual impurities. |
| Microbial Limits | Plate Count Method (USP/EP Methods) | Tests for total aerobic microbial count, molds and yeasts, and specified pathogens (e.g., Escherichia coli) according to pharmacopoeial requirements. Applicable for non-sterile active pharmaceutical ingredients to ensure biological safety. |
| Particle Size Distribution (if applicable) | Laser Diffraction (Particle Size Analyzer) | For powdered products, particle size distribution (D10, D50, D90) is measured to ensure process consistency, influencing dissolution rate and uniformity in formulation blending. |
| Thermal Stability / Melting Point | Differential Scanning Calorimetry (DSC) | Analyzes the melting/decomposition peak temperature of the sample (typically decomposes at 150–180 °C) to evaluate thermal stability and detect impurities or changes in hydrate forms. |
| Residual Solvents | Gas Chromatography (GC) | Using headspace or direct injection, detects residual organic solvents such as ethanol, acetone, and dichloromethane, ensuring compliance with ICH Q3C limits (e.g., ethanol ≤ 5000 ppm). |
Technical Specifications of Sodium L-ascorbyl-2-phosphate
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Optical Rotation | +52.0° to +54.0° (c=1, H2O) |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Sodium L-ascorbyl-2-phosphate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Sodium L-ascorbyl-2-phosphate
Safety Information of Sodium L-ascorbyl-2-phosphate
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Sodium L-ascorbyl-2-phosphate
Industrial Sodium L-ascorbyl-2-phosphate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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