China Factory Direct
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| CAS number | 66211-46-9 |
| Product name | (R)-3-Amino-1,2-propanediol |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral drug intermediates for synthesizing β-blockers (e.g., (S)-metoprolol) and antiviral agents | Chiral resolution or asymmetric synthesis, followed by protection, acylation, and coupling to install the target molecular scaffold |
| Pharmaceuticals | Key chiral intermediate for fingolimod, a drug used to treat multiple sclerosis | Condensation with 2-substituted benzoxazole derivatives to construct the chiral amino alcohol side chain of fingolimod |
| Agrochemicals | Synthetic precursor for novel chiral insecticides and fungicides | Used as a chiral auxiliary in asymmetric epoxidation or hydroxylation reactions to enhance enantioselectivity of the active isomer |
| Materials | Building block for liquid crystal monomers and chiral dopants | Introduced at the terminus of liquid crystal molecules via etherification or esterification to modulate phase transition temperature and helical twisting power |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC with Chiral Column | Separation and quantification of (R)-enantiomer using chiral stationary phase and UV detection. |
| Enantiomeric Excess (ee) | Chiral GC or Chiral HPLC | Direct comparison of peak areas of (R)- and (S)-enantiomers on a chiral column. |
| Water Content | Karl Fischer Titration | Electrochemical titration based on iodine consumption in presence of water. |
| Residue on Ignition | Gravimetric Analysis | Weighing residue after high-temperature ashing to determine inorganic impurities. |
| Heavy Metals | ICP-OES | Quantification of metal impurities (e.g., Pb, Cd, Ni) by atomic emission spectroscopy. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride anions in aqueous solution. |
| Sulfate Impurity | Ion Chromatography | Separation and conductivity detection of sulfate anions in aqueous solution. |
| Related Substances | Reverse-phase HPLC | Detection and quantification of structurally related organic impurities using UV detection. |
| Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral compound in solution. |
| pH (10% w/v aqueous solution) | pH Meter | Potentiometric measurement using calibrated glass electrode in standardized aqueous solution. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against specified standards under controlled lighting. |
| Solvent Residues | GC-FID | Quantification of residual solvents (e.g., methanol, acetone) using flame ionization detection. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | +2.0 to +4.0 deg (c=1, H2O) |
| Melting Point | 55 to 60 °C |
| Identification (NMR) | Conforms to reference spectrum |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.