China Factory Direct
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| CAS number | 6627-53-8 |
| Product name | 5-CHLORO-2-NITROANISOLE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticide Manufacturing | Key intermediate in the synthesis of the insecticide chlorpyrifos | Produced via nitration, chlorination, and methylation, then converted to chlorpyrifos through ammonolysis and cyclization |
| Pharmaceutical Manufacturing | Aromatic heterocyclic intermediate for synthesizing anti-inflammatory and antimicrobial agents | Serves as a substituted benzene ring precursor for constructing benzimidazole or benzoxazole drug scaffolds, participating in nucleophilic substitution or reductive cyclization reactions |
| Dye Manufacturing | Diazonium component intermediate for synthesizing azo dyes and triarylmethane dyes | After diazotization, coupled with coupling components (e.g., N,N-diethylaniline) to yield colored dyes |
| Organic Synthesis | Multifunctional aromatic building block for preparing fine chemicals containing chloro, nitro, or methoxy functional groups | Converted into various functionalized benzene derivatives via selective nitro group reduction, chloro group substitution, or demethylation |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities (e.g., isomers, nitro-reduction products, chlorination by-products) using gradient HPLC-UV against qualified impurity standards. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, dichloromethane, toluene) based on calibrated external standards. |
| Moisture Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine water content via stoichiometric reaction with iodine and sulfur dioxide. |
| Heavy Metals (as Pb) | ICP-OES | Multi-element quantification after acid digestion, measuring emission intensities of metal elements at characteristic wavelengths. |
| Chloride Ion Impurity | Ion Chromatography | Separation and conductivity detection of chloride anions in aqueous extract; quantified against sodium chloride calibration curve. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement by observing solid-to-liquid phase change in a capillary tube under controlled heating rate. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of visible particulates or discoloration against established reference samples under controlled lighting. |
| Acid Value | Acid-Base Titration | Titration with standardized potassium hydroxide solution to neutralize acidic impurities; endpoint detected potentiometrically or with phenolphthalein. |
| Residue on Ignition | Gravimetric Analysis | Weighing of non-volatile residue remaining after high-temperature ashing (700-800 C) of sample in a platinum crucible. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity as a function of angle to determine volume-based particle size distribution in dispersed dry powder. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through a solution in a standardized cell at specified concentration and wavelength (589 nm). |
| Test Item | Specification |
|---|---|
| Appearance | White to yellow powder, crystals, and/or chunks |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 68–72°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.