5'-Deoxy-5-fluorocytidine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 66335-38-4 |
| Product name | 5'-Deoxy-5-fluorocytidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5'-Deoxy-5-fluorocytidine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5'-Deoxy-5-fluorocytidine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5'-Deoxy-5-fluorocytidine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for antitumor drugs; used in the synthesis of fluoropyrimidine-based anticancer agents such as capecitabine | Serves as a key intermediate in the capecitabine synthesis pathway, undergoing multiple chemical modifications including protection, acylation, and deprotection |
Manufacturing Quality Control of 5'-Deoxy-5-fluorocytidine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 265 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time relative to reference standards or threshold reporting. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., methanol, acetonitrile) against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine water content via stoichiometric reaction with water. |
| Heavy Metals | ICP-MS | Inductively coupled plasma mass spectrometry for simultaneous quantification of elemental impurities (e.g., Pb, Cd, As, Hg) at trace levels. |
| Residue on Ignition | Gravimetric Analysis | Heating sample to 700-800 C to volatilize organic matter, then weighing inorganic residue as sulfate ash. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to confirm chiral integrity and enantiomeric purity. |
| pH of Solution | Potentiometric pH Measurement | Determination of pH in aqueous solution (10 mg/mL) using calibrated glass electrode and pH meter. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample to determine D10, D50, D90 values based on light scattering intensity vs. particle size. |
| Microbial Limits | Membrane Filtration | Quantitative enumeration of aerobic microorganisms and absence testing for specified pathogens per pharmacopeial methods. |
| Endotoxins | Kinetic Chromogenic LAL Assay | Quantification of bacterial endotoxins using Limulus amebocyte lysate reagent, measuring rate of color development proportional to endotoxin concentration. |
| Crystal Form | XRPD | Identification and verification of crystalline phase by comparing diffraction pattern to reference standard using Cu-Ka radiation. |
Technical Specifications of 5'-Deoxy-5-fluorocytidine
| Test Item | Specification |
|---|---|
| Appearance | White powder |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | +14.0 to +16.0 deg (c=1, in water) |
| Melting Point | 220 to 225 °C (decomposes) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5'-Deoxy-5-fluorocytidine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5'-Deoxy-5-fluorocytidine
Packaging of 5'-Deoxy-5-fluorocytidine
Industrial 5'-Deoxy-5-fluorocytidine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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