China Factory Direct
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| CAS number | 6635-31-0 |
| Product name | 6-Hydroxy-5-nitronicotinic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Synthesis of specific structural motifs in drug molecules | Bromination, nitration, hydrolysis, esterification, etc. |
| Agrochemical Intermediates | Synthesis of active ingredients for insecticides, fungicides, etc. | Oxidation, halogenation, acylation, etc. |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Inspect the sample by eye for color, physical state (e.g., white to off-white crystalline powder), and presence of foreign particles to determine compliance with specifications. |
| Identification | Infrared Spectroscopy (IR) High-Performance Liquid Chromatography (HPLC) |
IR: Measure the infrared absorption spectrum of the sample and compare it with a reference spectrum to confirm the presence of characteristic functional groups (e.g., nitro, carboxyl, hydroxyl, pyridine ring). HPLC: Compare the retention time of the test sample with that of the reference standard under specified chromatographic conditions. |
| Assay | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with a mobile phase consisting of a suitable mixture of buffer and organic solvent (e.g., phosphate buffer-methanol or acetonitrile). Detection is performed using a UV detector, typically at 254 nm or at the compound’s maximum absorbance wavelength. The assay is calculated using an external standard method. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Employ either gradient or isocratic elution to separate the main peak from potential impurities (e.g., starting materials, intermediates, degradation products). Individual and total impurity levels are controlled using area normalization or a corrected principal component self-reference method. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Constant Temperature Atmospheric Drying | Dry the sample at a specified temperature (e.g., 105°C) until constant weight is achieved. The percentage weight loss is measured to control moisture and volatile substances. |
| Sulfated Ash (Residue on Ignition) | High-Temperature Incineration | The sample is charred and then ignited in a high-temperature furnace at 700–800°C. The weight of the residual inorganic matter is measured to assess inorganic impurities (e.g., metal salts). |
| Residual Solvents | Gas Chromatography (GC) | Using headspace or direct injection, separate components on a capillary column and detect with an FID. Measures residual organic solvents (e.g., methanol, ethanol, dichloromethane) possibly remaining from manufacturing. Limits are controlled according to ICH Q3C guidelines. |
| pH Value | pH Meter Method | Prepare an aqueous solution of defined concentration (e.g., 1% w/v) and measure its pH using a calibrated pH meter, reflecting the ionization characteristics of carboxylic acid and phenolic hydroxyl groups. |
| Melting Point | Capillary Melting Point Method | Determine the temperature range from initial melting to complete melting using a melting point apparatus. Serves as an auxiliary indicator of purity and crystal form. |
| Test Item | Specification |
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| Appearance | Light yellow to yellow powder or crystals |
| Purity | >=98.0% (HPLC) |
| Melting Point | 215–220 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.