5-Hydroxymethylpyrrolidin-2-one Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 66673-40-3 |
| Product name | 5-Hydroxymethylpyrrolidin-2-one |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5-Hydroxymethylpyrrolidin-2-one
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5-Hydroxymethylpyrrolidin-2-one Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5-Hydroxymethylpyrrolidin-2-one
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Chiral Drug Intermediates | Used in the synthesis of chiral drug molecules, e.g., as a precursor in the synthesis of γ-aminobutyric acid (GABA) analogues or their derivatives, and employed in organic synthesis reactions for chiral pharmaceuticals. |
| Pharmaceutical Industry | Peptide Synthesis Modification | Serves as an alternative structural unit to proline or hydroxyproline for peptide chain modification, enhancing metabolic stability or bioavailability of peptide therapeutics. |
| Chemical Industry | Chiral Auxiliary | Functions as a chiral source or chiral auxiliary reagent in asymmetric synthesis reactions to induce formation of specific stereochemistry in the product. |
| Biochemistry | Enzyme Inhibitor Research | Used in biochemical studies as a potential inhibitor or structural analogue of certain metabolic enzymes (e.g., GABA transaminase) for investigating enzyme mechanisms. |
| Materials Science | Functional Polymer Monomer | Employed in the synthesis of biocompatible or biodegradable polymer materials, incorporated as a functional monomer into the polymer backbone. |
Manufacturing Quality Control of 5-Hydroxymethylpyrrolidin-2-one
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC with Chiral Column | Enantioselective separation and quantification using a chiral stationary phase and UV detection. |
| Specific Optical Rotation | Polarimetry | Measurement of the angle of rotation of plane-polarized light induced by the chiral compound in solution. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration based on the stoichiometric reaction of water with iodine and sulfur dioxide in pyridine/methanol medium. |
| Residue on Ignition | Gravimetric Analysis | Heating to 700-800 C to volatilize organic matter, followed by weighing of inorganic residue. |
| Heavy Metals | ICP-OES | Quantification of trace metal impurities (e.g., Pb, Cd, Hg, As) after acid digestion and plasma excitation. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride ions in aqueous extract. |
| Related Substances | HPLC with UV Detection | Separation and relative quantification of structurally similar impurities using reversed-phase chromatography. |
| Residual Solvents | GC-FID | Gas chromatographic separation with flame ionization detection for common solvents (e.g., methanol, acetone, ethyl acetate). |
| pH (1% w/v aqueous solution) | Potentiometric pH Measurement | Determination of hydrogen ion activity using calibrated glass electrode in aqueous solution. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against standard references under controlled lighting. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, indicating purity and identity. |
| Specific Gravity | Digital Density Meter | Measurement of density relative to water at specified temperature using oscillating U-tube principle. |
Technical Specifications of 5-Hydroxymethylpyrrolidin-2-one
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (GC-MS) |
| Optical Rotation | -33.0 to -27.0 deg (c=1, in methanol) |
| Melting Point | 58.0 to 62.0 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5-Hydroxymethylpyrrolidin-2-one
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5-Hydroxymethylpyrrolidin-2-one
Safety Information of 5-Hydroxymethylpyrrolidin-2-one
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 5-Hydroxymethylpyrrolidin-2-one
Industrial 5-Hydroxymethylpyrrolidin-2-one Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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