BOC-L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 66863-43-2 |
| Product name | BOC-L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for BOC-L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk BOC-L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of BOC-L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Key intermediate in peptide drug synthesis | Serves as a conformationally restricted amino acid building block for solid-phase or solution-phase peptide synthesis to construct drug molecules containing the tetrahydro-β-carboline moiety. |
| Pharmaceutical Chemicals | Anticancer drug development | Used as a scaffold—leveraging its indole-fused dihydropyridine structure—for structural modification and derivatization in developing topoisomerase inhibitors or DNA intercalators. |
| Pharmaceutical Chemicals | Synthesis of central nervous system (CNS) drugs | Serves as a precursor in synthesizing β-carboline derivatives with sedative, anxiolytic, or antidepressant activity. |
| Scientific Research | Asymmetric synthesis and chiral studies | Utilized as a chiral source or ligand precursor—exploiting the stereochemical specificity of its chiral carbon—for mechanistic studies in asymmetric catalysis. |
| Biochemistry | Enzyme inhibitor development | Serves as a structural template—based on the indole alkaloid scaffold—for designing and synthesizing novel enzyme inhibitors to modulate enzymatic activity and support drug screening. |
Manufacturing Quality Control of BOC-L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 220-280 nm, comparing peak area to reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally similar impurities using gradient HPLC-UV; identification via retention time matching and/or spiking. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., methanol, ethyl acetate) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines water content via coulometric or volumetric titration using iodine-based redox reaction in anhydrous medium. |
| Heavy Metals | ICP-MS | Quantifies trace metal impurities (e.g., Pb, Cd, Ni) after acid digestion using inductively coupled plasma mass spectrometry. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction. |
| Optical Rotation | [alpha]D Measurement | Measures specific optical rotation at 589 nm using sodium D-line to confirm chiral integrity and enantiomeric purity. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated capillary apparatus per USP <741>. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic ash content after high-temperature incineration (600-800 C) and weighing of residual residue. |
| Particle Size Distribution | Laser Diffraction | Analyzes particle size distribution in suspension using Mie scattering theory and laser diffraction instrumentation. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Measures hydrogen ion activity in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode. |
| Microbial Limits | Membrane Filtration | Quantifies aerobic microorganisms and detects specified pathogens (e.g., E. coli) using membrane filtration followed by agar culture. |
Technical Specifications of BOC-L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (by LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 210–215 °C |
| Optical Rotation | +15.0 to +18.0 ° (c=1, in DMF) |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of BOC-L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of BOC-L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID
Safety Information of BOC-L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of BOC-L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID
Industrial BOC-L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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