H-D-LEU-OME HCL Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 66866-69-1 |
| Product name | H-D-LEU-OME HCL |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for H-D-LEU-OME HCL
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk H-D-LEU-OME HCL Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of H-D-LEU-OME HCL
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral synthetic intermediate for the preparation of antibiotics and peptide-based drugs | Prepared via N-methylation of L-leucine followed by hydrochloride salt formation; used in subsequent asymmetric synthesis or solid-phase peptide synthesis |
| Chemical Synthesis | Chiral auxiliary or ligand in asymmetric catalytic reactions | Serves as a chiral source in organic synthesis, participating in transition metal-catalyzed allylation, hydrogenation, and related reactions |
| Biochemical Research | Peptide structure modification and conformational studies | Introduced into peptide chains via solid-phase peptide synthesis (SPPS) as a non-natural amino acid residue to investigate stereochemical effects |
Manufacturing Quality Control of H-D-LEU-OME HCL
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC with UV detection | Quantification based on peak area comparison against a certified reference standard using reversed-phase chromatography. |
| Chiral Purity | Chiral HPLC | Separation of enantiomers on a chiral stationary phase, with detection and quantitation of L-isomer content. |
| Loss on Drying | Gravimetric analysis (105 C, 2 h) | Mass loss measured after drying under controlled temperature and time to determine volatile content including residual solvents and water. |
| Residual Solvents | GC-FID | Separation and quantitation of common organic solvents (e.g., methanol, ethyl acetate) using gas chromatography with flame ionization detection. |
| Heavy Metals | ICP-OES | Multi-element quantitation of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, based on atomic emission intensities. |
| Chloride Content | Potentiometric titration with AgNO3 | Titration with silver nitrate using a silver indicator electrode; endpoint detected by potential change due to AgCl precipitation. |
| pH (1% aqueous solution) | pH meter measurement | Direct potentiometric measurement of hydrogen ion activity in a standardized aqueous solution at 25 C. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral molecules in solution, used to confirm stereochemical integrity. |
| Related Substances | HPLC with gradient UV detection | Separation and quantitation of structurally similar impurities (e.g., N-methyl-leucine isomers, degradants) using optimized gradient elution. |
| Water Content | Karl Fischer titration | Volumetric or coulometric determination of water via stoichiometric reaction with iodine, sulfur dioxide, and base in anhydrous medium. |
| Microbial Limits | Membrane filtration followed by colony counting | Enumeration of aerobic bacteria, yeasts, and molds after filtration, incubation on appropriate agar media, and colony enumeration. |
| Appearance (Solid) | Visual inspection | Assessment of physical state, color, and presence of foreign particles or discoloration under controlled lighting conditions. |
Technical Specifications of H-D-LEU-OME HCL
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 178-182°C |
| Optical Rotation | -15.0° to -19.0° (c=1, 1M HCl) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of H-D-LEU-OME HCL
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of H-D-LEU-OME HCL
Packaging of H-D-LEU-OME HCL
Industrial H-D-LEU-OME HCL Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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