6-Fluoro-4-chromanone Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 66892-34-0 |
| Product name | 6-Fluoro-4-chromanone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 6-Fluoro-4-chromanone
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 6-Fluoro-4-chromanone Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 6-Fluoro-4-chromanone
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Used in the synthesis of fluoroquinolone antibacterial agents and anti-inflammatory compounds | Serves as a key building block in multistep organic synthesis, including nucleophilic substitution and cyclization reactions |
| Organic Synthesis | Constructs fluorinated heterocyclic structural units | Introduces the fluorochromone scaffold via Friedel–Crafts acylation, Michael addition, and related reactions |
| Drug Discovery | Serves as a lead compound for structural modification to optimize biological activity | Employs structure–activity relationship (SAR) studies to derivatize the 6-fluoro and 4-carbonyl positions |
Manufacturing Quality Control of 6-Fluoro-4-chromanone
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-DAD | Separation and identification of impurities by HPLC coupled with diode array detection, using gradient elution and spectral comparison. |
| Residual Solvents | GC-FID | Quantification of volatile organic solvents (e.g., acetone, methanol) by gas chromatography with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration | Electrochemical titration measuring water via iodine-sulfur dioxide reaction in pyridine-methanol medium. |
| Heavy Metals | ICP-MS | Multi-element trace metal quantification (e.g., Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma mass spectrometry. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using suppressed conductivity detection with anion-exchange column. |
| Residue on Ignition | Gravimetric Analysis | Measurement of non-volatile inorganic residue after incineration at 700-800 C and subsequent weighing. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid phase transition temperature using calibrated capillary tube method per USP <741>. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral centers in solution at specified concentration and wavelength (e.g., 589 nm). |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against established reference standards under controlled lighting conditions. |
| pH of Aqueous Suspension | pH Meter | Measurement of hydrogen ion activity in a defined suspension (e.g., 1% w/v in water) using calibrated glass electrode. |
| Particle Size Distribution | Laser Diffraction | Analysis of size distribution based on angular variation of laser light scattering intensity from dispersed particles in liquid medium. |
Technical Specifications of 6-Fluoro-4-chromanone
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 124–128°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 6-Fluoro-4-chromanone
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 6-Fluoro-4-chromanone
Packaging of 6-Fluoro-4-chromanone
Industrial 6-Fluoro-4-chromanone Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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