China Factory Direct
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| CAS number | 6704-31-0 |
| Product name | 3-Oxetanone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate for synthesizing β-lactam antibiotics (e.g., carbapenems) | Used as a cyclobutanone derivative in [2+2] cycloaddition reactions to construct the four-membered β-lactam core structure |
| Pharmaceuticals | Heterocyclic building block for preparing antitumor agents (e.g., temozolomide analogues) | Undergoes nucleophilic ring opening followed by alkylation or acylation to introduce an N-substituted 3-oxetanone side chain |
| Materials Science | Modification component for epoxy resin curing agents | Copolymerized with multifunctional amines or anhydrides to enhance crosslink density and thermal stability |
| Organic Synthesis | Precursor for chiral ligands and catalyst supports | Converted via asymmetric hydrogenation or enzymatic reduction into chiral 1,3-diol derivatives for ligand synthesis |
| Detection Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical state, and visible impurities under natural light or standard illumination. |
| Purity | Gas Chromatography (GC) | Separation using a capillary GC column with flame ionization detection (FID). Quantification is performed via area normalization or external standard method, suitable for volatile organic compounds analysis. |
| High-Performance Liquid Chromatography (HPLC) | Reverse-phase C18 column with UV detection (typically at 210–220 nm); mobile phase commonly acetonitrile-water system. Suitable for thermally unstable or highly polar samples. | |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | ¹H-NMR and ¹³C-NMR used to confirm molecular structure; characteristic signals include methylene protons on the ring (~4.5–5.0 ppm) and carbonyl carbon signal (~200 ppm). |
| Fourier Transform Infrared Spectroscopy (FT-IR) | Detects characteristic functional group absorption peaks, such as C=O stretching vibration (~1750–1780 cm⁻¹, typical range for cyclic esters/ketones) and C–O–C (~1100–1200 cm⁻¹). | |
| Mass Spectrometry (MS) | Electron impact (EI) or electrospray ionization (ESI) ionization methods; identification of molecular ion peak (m/z = 72 [M]⁺), combined with fragment analysis for structural verification. | |
| Moisture Content | Karl Fischer Titration (KF) | Determination of trace water content via coulometric or volumetric methods, suitable for quality control of moisture-sensitive compounds. |
| Residual Solvents | Gas Chromatography (GC) | Per ICH Q3C guidelines, detection of potentially residual organic solvents (e.g., methanol, ethanol, acetone, dichloromethane) during manufacturing using headspace sampling coupled with FID detection. |
| Acid Value / Impurity Acids | Acid-Base Titration | Titrate free acid impurities in the sample with standardized NaOH solution; acid value calculated as mg KOH/g, reflecting oxidation or hydrolysis extent. |
| Melting Point / Boiling Point | Melting Point Apparatus or Differential Scanning Calorimetry (DSC) | Determine melting temperature (for solids) or boiling point (for liquids); DSC provides phase transition information useful for assessing purity and crystalline form consistency. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Detection of elemental impurities such as lead, cadmium, mercury, and arsenic, meeting pharmacopeial or industrial standards limits. |
| Thermal Stability | Thermogravimetric Analysis (TGA) | Monitor mass changes under programmed heating conditions to evaluate decomposition temperature and volatility, providing insight into storage stability. |
| Test Item | Specification |
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| Appearance | Pale-yellow liquid |
| Purity | >=98.0% (GC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Odor | Characteristic odor |
| Refractive Index (n20/D) | 1.420–1.430 |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.