China Factory Direct
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| CAS number | 67460-86-0 |
| Product name | 3,5-Dibromo-1H-pyrazole |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a pharmaceutical intermediate in the synthesis of biologically active nitrogen-containing heterocyclic compounds | Introduces the pyrazole moiety via organic synthesis methods such as nucleophilic substitution and coupling reactions |
| Agrochemicals | Used as an agrochemical intermediate in the synthesis of novel insecticides or fungicides | Constructs the target molecular scaffold through functional group transformations of bromopyrazole |
| Materials Science | Used to prepare nitrogen-containing functional materials, such as ligands or organic semiconductor precursors | Builds conjugated systems via metal-catalyzed coupling reactions (e.g., Suzuki, Sonogashira) leveraging the reactivity of the bromine atom |
| Test Item | Common Testing Methods | Method Overview |
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| Appearance | Visual Inspection | Observe the color, state, and visible impurities of the sample. It is usually a white to pale white crystalline powder. |
| Purity | High-Performance Liquid Chromatography (HPLC) | Use a reverse-phase C18 column with a UV detector (e.g., 254 nm). Identify by retention time and quantify by peak area to calculate the purity of the main component. |
| Content Determination | HPLC external standard method or internal standard method | Establish a standard curve using reference standards to determine the accurate content of 3,5-dibromopyrazole in the sample, commonly used for quantitative analysis of active pharmaceutical ingredients. |
| Structure Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Confirm the molecular structure using ¹H-NMR and ¹³C-NMR spectra, with characteristic peaks matching the chemical shifts of 3,5-dibromopyrazole. |
| Structure Confirmation | Mass Spectrometry (MS) | Determine the molecular ion peak using EI-MS or ESI-MS to verify the molecular weight (theoretical value: approximately 235.8 Da). |
| Melting Point | Melting Point Apparatus Method | Use an automatic or capillary melting point apparatus to determine the melting temperature, and compare it with literature values (usually around 120–122°C). |
| Moisture | Karl Fischer Titration | Determine the moisture content of the sample, suitable for evaluating storage stability and process control. |
| Residual Solvents | Gas Chromatography (GC) | Detect residual organic solvents (such as methanol, ethanol, acetone, dichloromethane, etc.) from the production process, complying with ICH limits. |
| Related Substances (Impurities) | HPLC Method | Separate and detect synthetic by-products or degradation impurities through gradient elution, to evaluate the impurity profile and total impurity level. |
| Crystal Form Analysis | X-ray Diffraction (XRD) | Analyze the crystal structure of solid samples to confirm the consistency of the crystal form, used for quality control of polymorphic substances. |
| Particle Size Distribution | Laser Diffraction Method | Determine the particle size distribution of the powder, which affects solubility and formulation performance, especially important in formulation development. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 124–128°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.