China Factory Direct
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| CAS number | 675112-70-6 |
| Product name | 4,4-DIFLUOROCYCLOHEXYLAMINE HYDROCHLORIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of antiviral agents (e.g., HCV NS5A inhibitors) | Introduces fluorinated cyclohexylamine structural units via nucleophilic substitution, reductive amination, or coupling reactions |
| Agrochemicals | Used to synthesize novel fluorinated pesticide molecules to enhance biological activity and metabolic stability | Serves as a building block for constructing fluorinated heterocycles or aliphatic amine-based active ingredients |
| Organic Synthesis | Fluorinated building block for constructing molecules with defined stereochemistry and electronic properties | Participates in amine-introduction steps within multistep syntheses, commonly applied in palladium-catalyzed cross-coupling or amidation reactions |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 210 nm, comparing peak area to certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities by gradient HPLC with UV detection, using relative response factors or external standards. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., methanol, acetone, ethyl acetate) by headspace GC with flame ionization detection against calibration curves. |
| Water Content | Karl Fischer Titration | Determines water by coulometric or volumetric titration using iodine generation in pyridine-free reagent, based on stoichiometric reaction with water. |
| Chloride Content | Potentiometric Titration | Quantifies chloride ions using silver nitrate titrant and silver/silver chloride indicator electrode, detecting endpoint via potential inflection. |
| Heavy Metals | ICP-OES | Simultaneously measures trace metals (Pb, Cd, Hg, As, Ni) after acid digestion by optical emission spectroscopy at element-specific wavelengths. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after controlled ashing at 550-600 C, expressed as percentage of initial sample mass. |
| Optical Rotation | Polarimetry | Determines specific rotation using sodium D-line light through a solution in specified solvent and concentration, indicating chiral purity. |
| pH of Aqueous Solution | pH Meter Measurement | Measures hydrogen ion activity in a 1% w/v aqueous suspension using calibrated glass electrode pH meter at 25 C. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry powder particle size by measuring angular variation in laser light scattering intensity and fitting to Mie theory. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated capillary tube method per USP <741>. |
| Microbial Limits | Membrane Filtration | Quantifies aerobic bacteria and molds/yeasts by filtering sample solution, culturing on TSA and SDA, and counting colony-forming units. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 210–215 °C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.