1H-INDAZOLE-4-CARBOXYLIC ACID Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 677306-38-6 |
| Product name | 1H-INDAZOLE-4-CARBOXYLIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1H-INDAZOLE-4-CARBOXYLIC ACID
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1H-INDAZOLE-4-CARBOXYLIC ACID Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1H-INDAZOLE-4-CARBOXYLIC ACID
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Key intermediate for novel kinase inhibitors, used in structural modification of antitumor agents (e.g., BTK and ALK inhibitors) | Under inert atmosphere, undergoes condensation with acyl chlorides or acid anhydrides, or is converted to amide derivatives via esterification followed by aminolysis |
| Agrochemical R&D | Potential molecular scaffold for fungicides and insecticides, used to construct nitrogen-containing heterocyclic active ingredients | Introduces aryl or alkenyl side chains via palladium-catalyzed cross-coupling (e.g., Suzuki or Heck reactions), followed by oxidation or hydrolysis to optimize bioactivity |
| Materials Science | Functional dopant component in the hole-transport layer of organic light-emitting diodes (OLEDs) | Co-evaporated with triarylamine-based compounds to form thin films, or processed into homogeneous thin films via solution-based spin coating |
Manufacturing Quality Control of 1H-INDAZOLE-4-CARBOXYLIC ACID
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 254 nm, comparing peak area to calibrated standard. |
| Related Substances | HPLC-UV | Detects and quantifies impurities by separation on C18 column with gradient elution and UV detection. |
| Residual Solvents | GC-FID | Identifies and quantifies volatile organic solvents using gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Measures water via coulometric or volumetric titration based on iodine consumption in pyridine-methanol buffer. |
| Heavy Metals | ICP-MS | Determines trace metal contaminants (e.g., Pb, Cd, Hg) by plasma ionization and mass spectrometric detection. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride anion using suppressed conductivity detection after anion-exchange separation. |
| Sulfate Impurity | Ion Chromatography | Quantifies sulfate anion via anion-exchange chromatography with conductivity detection. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature ashing at 700-800 C. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using controlled heating and visual observation. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles under controlled white light against standard references. |
| Bulk Density | USP <616> Tap Density Method | Measures mass per unit volume after standardized tapping to assess powder flow and packing behavior. |
| pH of Aqueous Suspension | pH Meter | Determines acidity/basicity of a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode. |
Technical Specifications of 1H-INDAZOLE-4-CARBOXYLIC ACID
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 192–196 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1H-INDAZOLE-4-CARBOXYLIC ACID
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1H-INDAZOLE-4-CARBOXYLIC ACID
Safety Information of 1H-INDAZOLE-4-CARBOXYLIC ACID
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 1H-INDAZOLE-4-CARBOXYLIC ACID
Industrial 1H-INDAZOLE-4-CARBOXYLIC ACID Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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