China Factory Direct
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| CAS number | 67861-96-5 |
| Product name | NALPHA-tert-Butoxycarbonyl-L-norvaline |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Chiral building block for synthesizing valine-containing peptide drugs or intermediates | Participates in coupling reactions as a protected amino acid in solid-phase or solution-phase peptide synthesis |
| Organic Synthesis | Boc-protected L-norvaline derivative serving as a stereoselective building block | Deprotection of the Boc group under basic conditions, followed by amide bond formation or cyclization |
| Biochemical Research | Preparation of sequence-specific modified peptides to study protein structure–function relationships | Incorporated into target peptide chains via standard Fmoc/Boc strategies |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (BOC-L-norvaline dicyclohexylamine salt) | HPLC with UV detection | Quantifies main component using reverse-phase HPLC and UV absorbance at characteristic wavelength. |
| Related Substances | HPLC with UV detection | Separates and quantifies structurally related impurities using gradient elution and UV detection. |
| Residual Solvents | GC-FID | Detects and quantifies volatile organic solvents (e.g., THF, toluene) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer titration | Determines trace water via coulometric or volumetric titration with iodine-based reagent. |
| Heavy Metals | ICP-OES | Measures total heavy metal content (e.g., Pb, Cd, Ni) after acid digestion using inductively coupled plasma optical emission spectroscopy. |
| Residual Catalyst (Pd) | ICP-MS | Quantifies palladium residue at sub-pptr levels using inductively coupled plasma mass spectrometry. |
| Optical Rotation | [alpha]D measurement | Measures specific rotation using sodium D-line light to confirm chiral integrity and enantiomeric purity. |
| pH of Aqueous Suspension | Potentiometric pH measurement | Determines pH of a standardized suspension in water to assess acid-base balance and salt stability. |
| Loss on Drying (LOD) | Gravimetric thermogravimetry | Determines volatile content by weight loss after controlled heating under defined temperature and time. |
| Particle Size Distribution | Laser diffraction | Measures particle size distribution in dry or dispersed state using Mie scattering theory. |
| Appearance | Visual inspection | Assesses physical form, color, and homogeneity against established reference standard under controlled lighting. |
| Residue on Ignition | Gravimetric ash test | Quantifies inorganic residue remaining after high-temperature ignition of sample. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142-146°C |
| Optical Rotation | -15.0° to -17.0° (c=1, in 1M HCl) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.