China Factory Direct
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| CAS number | 67914-60-7 |
| Product name | 4-(1-Acetylpiperazin-4-yl)phenol |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a pharmaceutical intermediate in the synthesis of antidepressant and anti-anxiety agents | Prepared via acylation and coupling reactions of piperazine derivatives |
| Biomedical Research | Applied in the synthesis of novel targeted therapeutics or probe molecules | Structurally modified through multi-step organic synthesis to introduce specific functional groups |
| Polymer Materials | Employed as a functional monomer to enhance thermal stability and biocompatibility of polymers | Incorporated into the polymer backbone via condensation or addition polymerization |
| Chemical Reagents | Utilized as a reference standard or analytical reagent for quality control and assay development | Purity and structure confirmed by high-performance liquid chromatography (HPLC) or nuclear magnetic resonance (NMR) |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection Method | Observe the sample's color, form (e.g., white or off-white crystalline powder), and check for any foreign substances or physical characteristics. |
| Identification | Infrared Spectroscopy (IR) | Confirm characteristic functional groups (e.g., amide, phenolic hydroxyl, piperazine ring) by comparing the sample's infrared absorption spectrum with that of a standard. |
| High-Performance Liquid Chromatography (HPLC) | The retention time matches that of the reference standard; used for preliminary chemical structure confirmation. | |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Determine the main component's peak area using external standard or internal standard method under specific chromatographic conditions to calculate content (typically ≥98.0%). |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Separate the main peak from impurity peaks using a gradient elution program, and calculate the content of each impurity by area normalization or self-comparison method. |
| Moisture | Karl Fischer Titration | Determine moisture content in the sample using volumetric or coulometric methods, within pharmacopoeia limits (e.g., ≤0.5%). |
| Residual Solvents | Gas Chromatography (GC) | Use headspace injection or direct injection to detect organic solvents potentially remaining from the synthesis process (e.g., methanol, ethyl acetate). |
| Melting Point | Capillary Melting Point Determination | Determine the temperature range at which the substance transitions from solid to liquid as an auxiliary indicator of purity and identity. |
| pH Value (Solution) | pH Meter Method | Dissolve the sample into a water solution of specified concentration and measure its pH value to evaluate acid-base stability or compatibility for formulations. |
| Heavy Metals | Atomic Absorption Spectrometry (AAS) or ICP-MS | Detect harmful metallic elements such as lead, cadmium, mercury, and arsenic residue, ensuring compliance with ICH Q3D or pharmacopoeia limit requirements. |
| Loss on Drying | Oven-Drying to Constant Weight Method | Dry the sample at a specified temperature (e.g., 105°C) until constant weight is achieved, and calculate the weight loss to reflect volatile components or adsorbed water content. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 124–128°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.