D-Cycloserine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 68-41-7 |
| Product name | D-Cycloserine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for D-Cycloserine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk D-Cycloserine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of D-Cycloserine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Antitubercular Agent | Used as a second-line antitubercular agent, either alone or in combination with other antitubercular drugs, to kill or inhibit the growth of Mycobacterium tuberculosis by suppressing bacterial cell wall synthesis. |
| Pharmaceutical Industry | Antibiotic Intermediate | Applied as a competitive inhibitor targeting alanine racemase and D-alanine ligase in bacterial peptidoglycan synthesis, leveraging its structural similarity to D-alanine. |
| Fine Chemicals | Chiral Synthesis Intermediate | Employed as a chiral source or chiral auxiliary in the synthesis of other optically active amino acid derivatives, peptides, or pharmaceutical intermediates. |
| Scientific Research | Neuroscience Research Tool Compound | Used as a partial agonist at the glycine site of the N-methyl-D-aspartate (NMDA) receptor to investigate learning and memory mechanisms, as well as therapeutic pathways for schizophrenia and anxiety disorders. |
| Pharmaceutical Industry | Drug Formulation Development | Applied in developing fixed-dose combinations for drug-resistant tuberculosis or as an adjunctive therapeutic agent for central nervous system disorders such as phobias and obsessive-compulsive disorder. |
Manufacturing Quality Control of D-Cycloserine
| Test Item | Common Test Methods | Method Overview |
|---|---|---|
| Identification | Infrared Spectroscopy (IR) | Determine the infrared absorption spectrum of D-cycloserine and compare it with the reference spectrum to confirm characteristic functional groups and molecular structure. |
| Specific Optical Rotation | Use a polarimeter to measure the specific optical rotation of a D-cycloserine aqueous solution to verify its optical purity and confirm the D-configuration. | |
| Assay | High-Performance Liquid Chromatography (HPLC) | Employ reversed-phase HPLC (typically using a C18 column) with a UV detector (e.g., 210 nm). Quantify D-cycloserine content using external or internal standard methods. |
| Related Substances (Impurity Testing) | High-Performance Liquid Chromatography (HPLC) | Use gradient or isocratic elution to separate and detect organic impurities in D-cycloserine (e.g., L-cycloserine, degradation products). Impurity levels are typically controlled by area normalization or main component self-dilution method. |
| Water Content | Karl Fischer Titration | Determine water content using volumetric or coulometric Karl Fischer titration. Suitable for D-cycloserine active pharmaceutical ingredient (API), which may be thermally unstable or hygroscopic. |
| Residual Solvents | Gas Chromatography (GC) | According to ICH Q3C guidelines, use headspace injection gas chromatography to detect residual organic solvents (e.g., methanol, ethanol, acetone) that may remain from the manufacturing process. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Determine total or individual heavy metal content (e.g., lead, cadmium, mercury, arsenic) to ensure compliance with pharmacopoeial limits. |
| pH Value | pH Meter Method | Prepare an aqueous solution of D-cycloserine at a specified concentration and measure its pH using a calibrated pH meter to assess whether acidity/alkalinity is within the specified range. |
| Solution Clarity and Color | Visual Turbidity/Color Comparison or UV-Visible Spectrophotometry | Compare the test solution visually with standard turbidity or color solutions, or measure absorbance at specific wavelengths to determine if the solution is clear and colorless or meets color limits. |
Technical Specifications of D-Cycloserine
| Test Item | Specification |
|---|---|
| Appearance | White to light yellow crystalline powder |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 216.0 to 220.0 °C |
| Optical Rotation | +110.0 to +130.0° (c=1, H2O) |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of D-Cycloserine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of D-Cycloserine
Packaging of D-Cycloserine
Industrial D-Cycloserine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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