1-ETHYL-7-CHLORO-6-FLUORO-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 68077-26-9 |
| Product name | 1-ETHYL-7-CHLORO-6-FLUORO-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 68077-26-9
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 68077-26-9 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 68077-26-9
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of quinolone antibiotics | Used to synthesize fluoroquinolone drugs such as levofloxacin and lomefloxacin, via cyclization and substitution reactions to construct the core quinolone structure |
| Fine Chemicals | Organic synthesis raw material | Serves as a building block for fluorinated quinoline compounds, participating in coupling and amidation reactions to produce functional molecules |
Manufacturing Quality Control of 68077-26-9
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 275 nm. |
| Related Substances | HPLC-DAD | Separation and detection of structurally related impurities using gradient HPLC with diode-array detection and threshold-based reporting per ICH Q3B. |
| Residual Solvents | GC-FID | Quantitative determination of Class 2 and 3 residual solvents (e.g., DMF, ethyl acetate) using headspace gas chromatography with flame ionization detection. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic elements (Pb, Cd, As, Hg, Ni) after acid digestion, based on USP <233> and ICH Q3D guidelines. |
| Chloride Content | Potentiometric Titration | Direct titration with silver nitrate using a silver indicator electrode; endpoint detected by potential inflection. |
| Loss on Drying | Gravimetric (Thermogravimetric) | Mass loss measured after drying at 105 C for 2 hours under vacuum, per USP <731>. |
| Residue on Ignition | Sulfated Ash (Gravimetric) | Inorganic residue mass determined after charring and incineration at 600 C in a platinum crucible. |
| Water Content | Karl Fischer Titration | Coulometric or volumetric determination of water via iodine-sulfur dioxide redox reaction in anhydrous methanol-based reagent. |
| Particle Size Distribution | Laser Diffraction | Measurement of size distribution in suspension using Mie scattering theory and hydrodynamic dispersion. |
| pH of Aqueous Slurry | pH Potentiometry | Measurement of hydrogen ion activity in a 1:10 w/v suspension in purified water using calibrated glass electrode. |
| Microbial Enumeration | Membrane Filtration | Quantification of aerobic mesophilic microorganisms per USP <61> after filtration, membrane transfer, and incubation on soybean-casein digest agar. |
| Crystallinity | XRPD | Qualitative and quantitative phase identification based on Bragg diffraction patterns compared to reference standards. |
Technical Specifications of 68077-26-9
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 218–222°C |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 68077-26-9
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 68077-26-9
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Industrial 68077-26-9 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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