Methyl 2-bromo-6-chlorobenzoate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 685892-23-3 |
| Product name | Methyl 2-bromo-6-chlorobenzoate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Methyl 2-bromo-6-chlorobenzoate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Methyl 2-bromo-6-chlorobenzoate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Methyl 2-bromo-6-chlorobenzoate
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate in the synthesis of anticancer agents (e.g., EGFR inhibitors) | Undergoes substitution with piperazine derivatives to construct the quinazoline scaffold |
| Pesticide R&D | Structural modification unit for novel insecticides and fungicides | Introduces heterocyclic groups via metal-catalyzed coupling reactions to optimize biological activity |
| Organic Synthesis | General building block for preparing polysubstituted benzoic acid derivatives | Subjected to functional group transformations—such as lithiation-borylation or lithiation-iodination—for use in cross-coupling reactions (e.g., Suzuki, Heck) |
Manufacturing Quality Control of Methyl 2-bromo-6-chlorobenzoate
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 220-254 nm based on peak area comparison to reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., isomers, hydrolysis/degradation products) using gradient HPLC-UV with suitable column and detection wavelength. |
| Residual Solvents | GC-FID | Measures trace organic solvents (e.g., methanol, dichloromethane) by gas chromatography with flame ionization detection using headspace sampling. |
| Water Content | Karl Fischer Titration | Determines water content via coulometric or volumetric titration using iodine generation and stoichiometric reaction with water. |
| Acid Value | Acid-Base Titration | Measures free acid content (if hydrolyzed) by titration with standardized NaOH solution using phenolphthalein or potentiometric endpoint detection. |
| Chlorine Content | Oxygen Flask Combustion followed by Ion Chromatography | Quantifies total chlorine after combustion in oxygen flask; chloride ions are measured by IC with conductivity detection. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Determines trace heavy metals after microwave-assisted acid digestion using inductively coupled plasma mass spectrometry for multi-element detection. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature ashing (500-600 C) and weighing of the cooled crucible. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary apparatus per USP/Ph. Eur. guidelines. |
| Optical Rotation | Polarimetry | Measures specific rotation using sodium D-line light to detect chiral impurities or enantiomeric excess (though compound is achiral, confirms absence of chiral contaminants). |
| Particle Size Distribution | Laser Diffraction | Analyzes dry or wet dispersion particle size distribution using Mie theory-based light scattering principles. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity against established reference standards under controlled lighting and viewing conditions. |
Technical Specifications of Methyl 2-bromo-6-chlorobenzoate
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (by LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 48–52°C |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Methyl 2-bromo-6-chlorobenzoate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Methyl 2-bromo-6-chlorobenzoate
Safety Information of Methyl 2-bromo-6-chlorobenzoate
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Methyl 2-bromo-6-chlorobenzoate
Industrial Methyl 2-bromo-6-chlorobenzoate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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