China Factory Direct
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| CAS number | 69320-89-4 |
| Product name | L-Isoleucine tert-butyl ester hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeIndustrial GradeSpecialty GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for synthesizing antibacterial agents | Used as a starting material to prepare antibacterial agents via multi-step organic synthesis |
| Pharmaceuticals | Key intermediate for antiviral drug manufacturing | Functional group transformation conducted under specific catalysis to generate the target antiviral compound |
| Food Additives | Production of functional food ingredients | Hydrolyzed and purified to yield amino acid derivatives required by the human body |
| Chemicals | Synthesis of chiral ligands or catalysts | Chemically modified to construct highly efficient chiral catalysts, leveraging its inherent chirality |
| Agriculture | Development of novel pesticide active ingredients | Condensed with other organic molecules to design highly selective pesticides |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantification using reversed-phase HPLC with UV detection at ~205 nm, comparing peak area against a certified reference standard. |
| Enantiomeric Purity | Chiral HPLC | Separation on a chiral stationary phase followed by UV detection to determine L-isoleucine enantiomer excess relative to D-isomer. |
| Residual Solvents (e.g., tert-butanol, DCM, ethyl acetate) | GC-FID | Headspace or direct injection GC with flame ionization detection, quantifying solvents against calibrated standards per ICH Q3C. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration with iodine-based reagent to determine trace water via stoichiometric reaction. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element quantification after acid digestion using inductively coupled plasma mass spectrometry for sub-ppb sensitivity. |
| Chloride Ion (Cl⁻) Impurity | Ion Chromatography (IC) | Separation on an anion-exchange column with suppressed conductivity detection, calibrated against NaCl standards. |
| Residual Tert-Butyl Carbamate (Boc-anhydride derivative) | HPLC-UV | Specific detection of Boc-related impurities using gradient HPLC-UV at 210–220 nm, validated per ICH Q2(R2). |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid-to-liquid phase transition occurs under controlled heating rate. |
| Appearance & Color | Visual Inspection / APHA Color Scale | Subjective visual assessment against water and standardized APHA color solutions for yellowness/browning. |
| Specific Optical Rotation | [α]D | Measurement of plane-polarized light rotation in solution using a digital polarimeter at 589 nm (Na-D line), reported per USP/EP guidelines. |
| Test Item | Specification |
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| Appearance | White solid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Melting Point | 128-132°C |
| Optical Rotation | +13.0 to +17.0° (c=1, in 6N HCl) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.