China Factory Direct
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| CAS number | 6999-19-5 |
| Product name | 6999-19-5 |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Organic Synthesis | Alkynol intermediates for constructing complex molecules containing silyl groups | Used as nucleophiles in transition metal-catalyzed reactions such as Sonogashira coupling and Heck reactions; silyl groups serve as hydroxyl protecting groups and are removed under mild conditions in subsequent deprotection steps (e.g., using TBAF) |
| Pharmaceutical R&D | Silyl-modified building blocks for potential drug molecules to improve pharmacokinetic properties | Introduction of trimethylsilylethynyl groups to enhance lipophilicity and metabolic stability; applied in synthesizing alkyne-containing targeted probes or prodrugs |
| Materials Science | Monomeric component for organic light-emitting diodes (OLEDs) and conjugated polymers | Applied in C–C coupling between terminal alkynes and aryl halides to construct silyl-functionalized π-conjugated frameworks, enabling tuning of energy levels and thin-film morphology |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detection | Quantifies main component peak area relative to calibrated standard using retention time matching and response factor correction. |
| Water Content | Karl Fischer Titration | Measures water via stoichiometric reaction between water, iodine, sulfur dioxide, and base in methanol medium. |
| Residue on Ignition | Gravimetric Analysis | Determines non-volatile inorganic impurities by ashing sample at 500-600 C and weighing residual mass. |
| Acidity (as HCl) | Acid-Base Titration with NaOH | Neutralizes acidic impurities using standardized sodium hydroxide solution and phenolphthalein endpoint detection. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-OES | Simultaneously quantifies trace metal contaminants after acid digestion by measuring element-specific atomic emission intensities. |
| Chloride Content | Ion Chromatography (IC) | Separates and quantifies chloride anions based on differential migration in ion-exchange column with conductivity detection. |
| Color (APHA) | Visual Comparison or Spectrophotometry | Evaluates yellowness/browning by comparing sample color to APHA platinum-cobalt standard scale using 430 nm absorbance. |
| Density at 20 C | Digital Density Meter | Measures mass per unit volume using oscillating U-tube principle with temperature-controlled sample cell. |
| Refractive Index at 20 C | Abbe Refractometer | Determines refractive index based on critical angle of total internal reflection at prism-sample interface. |
| Residual Solvents (e.g., THF, Hexane) | Headspace Gas Chromatography (HS-GC) | Quantifies volatile organic solvents by analyzing equilibrium vapor phase above heated sample using GC-FID. |
| Related Substances | GC-MS | Identifies and semi-quantifies structural analogs and degradation products via retention time and mass spectral library matching. |
| Optical Rotation | Polarimetry | Measures specific rotation using plane-polarized light deflection through chiral compound solution in controlled temperature cell. |
| Test Item | Specification |
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| Appearance | Colorless liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Refractive Index (n20/D) | 1.420–1.430 |
| Relative Density (20°C/25°C) | 0.82–0.84 g/cm³ |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.