China Factory Direct
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| CAS number | 70-18-8 |
| Product name | Glutathione |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeFood GradeCosmetic Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Antioxidant for detoxification and hepatoprotection | Used as an active pharmaceutical ingredient in oral or intravenous formulations |
| Pharmaceuticals | Adjunct therapy for chemotherapy-induced toxicity | Administered in combination with chemotherapeutic agents to mitigate oxidative stress via reduction |
| Pharmaceuticals | Treatment of liver diseases (e.g., hepatitis, cirrhosis) | Administered via intravenous infusion or oral formulations to support hepatocyte repair |
| Pharmaceuticals | Whitening and skin care ingredient | Applied topically in skincare products to inhibit melanin synthesis by suppressing tyrosinase activity |
| Food | Food antioxidant | Added to functional foods or dietary supplements to retard oxidation |
| Food | Nutritional fortificant | Incorporated into health foods as a glutathione precursor or active ingredient |
| Cosmetics | Anti-aging and skin-whitening ingredient | Formulated into emulsions and serums to inhibit melanin deposition via reduced glutathione |
| Biotechnology | Cofactor in enzymatic reactions | Maintains a reducing environment in in vitro enzymatic reaction systems to stabilize enzyme activity |
| Biotechnology | Additive for protein folding and purification | Added to recombinant protein expression systems to prevent incorrect disulfide bond formation |
| Agriculture | Plant stress resistance enhancer | Applied via foliar spray or root drench to improve crop tolerance to drought and salinity stress |
| Test Item | Common Detection Methods | Method Overview |
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| Content Determination | High-Performance Liquid Chromatography (HPLC) | Separates glutathione using a reverse-phase column, with UV or fluorescence detectors for quantification; high sensitivity and good reproducibility, recommended by pharmacopoeias. |
| Content Determination | Enzymatic Cycling Method (Enzyme-Promoted Colorimetric Method) | Relies on the reaction between glutathione reductase and DTNB to produce a yellow product, with absorbance measured at 412 nm to indirectly calculate GSH content; simple operation and low cost. |
| Content Determination | Spectrophotometry (DTNB Method) | Uses 5,5'-dithiobis(2-nitrobenzoic acid) (DTNB) to react with sulfhydryl groups to produce color, with absorbance measured at 412 nm; suitable for rapid screening of crude extracts. |
| Oxidized/Reduced Ratio | HPLC combined with electrochemical or fluorescent detection | Can simultaneously separate and quantify reduced glutathione (GSH) and oxidized glutathione (GSSG), assessing oxidative stress status; derivatization is required to improve sensitivity. |
| Purity Analysis | Thin Layer Chromatography (TLC) | Preliminary qualitative analysis of impurities, judged by Rf values; simple equipment but low resolution, commonly used in teaching or initial screening. |
| Purity and Impurity Analysis | High-Performance Liquid Chromatography-Mass Spectrometry (HPLC-MS) | High-resolution identification of glutathione and its related impurities or degradation products; suitable for complex systems or high-quality research requirements. |
| Stability/Degradation Product Detection | HPLC or CE (Capillary Electrophoresis) | Monitors the degradation of glutathione during storage or processing, such as conversion into GSSG or other derivatives; CE has high separation efficiency and requires small sample amounts. |
| Biological Activity Assessment | Cell Antioxidant Capacity Assay (e.g., DPPH/ABTS) | Reflects the biological activity of glutathione indirectly through its ability to scavenge free radicals; commonly used in quality evaluation of functional foods or health supplements. |
| Test Item | Specification |
|---|---|
| Appearance | White powder to crystal |
| Purity | >=98.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Optical Rotation | -16.0 to -19.0 deg (c=2, H2O) |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.