China Factory Direct
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| CAS number | 700-06-1 |
| Product name | Indole-3-carbinol |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeFood GradeCosmetic Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Anticancer drug development | Used as a signaling pathway modulator to study the relationship between estrogen metabolism and cancer |
| Pharmaceuticals | Anti-inflammatory and antioxidant agent development | Applied in mechanistic studies of inflammation-related diseases through modulation of the NF-κB and Nrf2 pathways |
| Cosmetics | Skin conditioning agent | Incorporated into anti-aging or skin-brightening formulations to regulate keratinocyte metabolism |
| Agriculture | Plant growth regulator research | Used to mimic the effects of natural indole compounds on plant development |
| Biochemical research | Cell signaling pathway probe | Employed as an aryl hydrocarbon receptor (AhR) agonist in in vitro assays |
| Nutritional supplements | Functional ingredient | Utilized as a raw material in dietary supplements to support hormonal balance and detoxification metabolism |
| Test Item | Common Analytical Methods | Method Overview |
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| Content Determination | High-Performance Liquid Chromatography (HPLC) | Using a C18 reversed-phase chromatography column, UV detector (typically 220–280 nm), with methanol/water or acetonitrile/water as the mobile phase, and external standard method for quantification. Suitable for precise determination of I3C content in raw materials and formulations. |
| Purity Analysis | HPLC-UV or HPLC-DAD | Utilizing a diode array detector (DAD) to obtain full wavelength spectra, identify impurity peaks, and calculate the purity of the main component, evaluating the overall sample purity. |
| Related Substances/Impurity Detection | HPLC-MS or HPLC-UV | Combined with mass spectrometry (MS) can identify the structure of unknown impurities; using high-sensitivity UV detector for quantification of known impurities (such as dimers, degradation products, etc.). |
| Moisture Content | Karl Fischer Titration Method | Determine trace moisture content by titration, ensuring product stability and preventing I3C from decomposing due to hygroscopy. |
| Residual Solvents | Gas Chromatography (GC-FID or GC-MS) | Headspace or direct injection, detecting residual organic solvents (such as methanol, ethanol, ethyl acetate, etc.) from synthesis or extraction processes, complying with ICH Q3C standards. |
| Heavy Metal Detection | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | High sensitivity simultaneous detection of multiple heavy metal elements (such as Pb, As, Cd, Hg, etc.), ensuring compliance with pharmacopoeia or food safety limit requirements. |
| Melting Point Determination | Capillary Melting Point Apparatus | Determine the melting range of solid I3C (literature value approximately 140–145°C), serving as a physical constant for identification and purity assessment. |
| Appearance and Physical Properties | Visual Observation and Physicochemical Testing | Observe color (white to off-white crystalline), odor, solubility (soluble in ethanol, DMSO, slightly soluble in water), etc., as basic characteristics. |
| Stability-Related Degradation Products | Accelerated Stability Testing + HPLC-MS | Investigate I3C degradation under conditions of high temperature, high humidity, and light exposure, combined with HPLC-MS to identify major degradation products (such as DIM, ICZ, etc.), guiding storage conditions. |
| Test Item | Specification |
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| Appearance | White crystalline solid |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 125–129 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.