China Factory Direct
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| CAS number | 701-27-9 |
| Product name | 3-FLUOROBENZENESULFONYL CHLORIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthetic intermediate for fluorinated drug molecules, including antidepressants and antitumor agents | Introduces the 3-fluorobenzenesulfonyl group via nucleophilic substitution to construct the active molecular scaffold |
| Agrochemicals | Synthesis of fluorinated sulfonamide herbicides or insecticides | Condenses with amine compounds to form the sulfonamide structure, conferring biological activity |
| Materials Science | Modified monomer for high-performance polymers (e.g., polysulfones, polyimides) | Acts as a sulfonylation reagent in polymerization reactions to enhance thermal stability or solubility |
| Organic Synthesis | Fluoroaryl sulfonylation reagent | Reacts with nucleophiles such as alcohols and amines under basic conditions to yield corresponding sulfonate esters or sulfonamides |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Purity | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase column with methanol/water or acetonitrile/water as mobile phase and a UV detector (e.g., 254 nm) to quantify the purity of the main component. Suitable for separation and quantification of trace impurities. |
| Assay | Gas Chromatography (GC) | Uses a capillary column (e.g., DB-5) and FID detector for quantification by internal standard method. Suitable for content analysis of volatile sulfonyl chloride compounds. |
| Water Content | Karl Fischer Titration | Determines trace water content in the sample by coulometric or volumetric method, preventing hydrolysis of sulfonyl chloride caused by moisture which may affect product quality. |
| Free Acid (e.g., HCl) | Acid-Base Titration | Titrates acidic substances (e.g., HCl) generated after sample hydrolysis using a standard NaOH solution to indirectly determine the content of free acid impurities. |
| Appearance and Color | Visual Color Comparison / Spectrophotometry | Compares with standard color solutions or measures absorbance at specific wavelengths to evaluate whether the product color meets the requirement of colorless to light yellow liquid. |
| Density | Density Meter / Pycnometer Method | Measures the density of the sample at a specified temperature (e.g., 20°C) as a physical constant to assist in determining product consistency. |
| Refractive Index | Abbe Refractometer Method | Measures the refractive index of the sample at 20°C for use in identification and batch consistency control. |
| Residual Solvents | Head-Space Gas Chromatography (HS-GC) | Uses headspace injection and GC-FID or GC-MS to detect residual organic solvents (e.g., dichloromethane, toluene), in compliance with ICH Q3C guideline. |
| Structure Confirmation | Proton Nuclear Magnetic Resonance (¹H NMR), Infrared Spectroscopy (IR) | ¹H NMR confirms characteristic peaks of molecular structure; IR confirms characteristic absorption peaks of sulfonyl chloride functional groups (~1370 cm⁻¹, ~1180 cm⁻¹). |
| Stability-Related Impurities | Accelerated Stability Testing + HPLC Monitoring | Stores the sample under high temperature and humidity conditions and samples periodically for HPLC analysis of degradation products (e.g., 3-fluorobenzenesulfonic acid) to evaluate storage stability. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Odor | Characteristic pungent odor |
| Refractive Index (n20/D) | 1.535–1.545 |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.