4-NITROTHIOANISOLE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 701-57-5 |
| Product name | 4-NITROTHIOANISOLE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-NITROTHIOANISOLE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-NITROTHIOANISOLE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-NITROTHIOANISOLE
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of the antifungal agent terbinafine | Used to construct the final molecular scaffold via nitro group reduction to amino, followed by diazotization and substitution |
| Pesticides | Structural building block for triazole fungicides such as fluxapyroxad | Applied as an aryl substituent in heterocycle construction, typically introduced into the target molecule via nitro reduction, diazotization, and coupling reactions |
| Dyes | Intermediate for azo and reactive dyes | Reacted with aromatic amines or phenols via diazotization-coupling to produce colored azo compounds |
Manufacturing Quality Control of 4-NITROTHIOANISOLE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at ~254 nm. |
| Related Substances | HPLC-UV or HPLC-DAD | Separation and identification of impurities (e.g., nitrophenol, anisole, sulfide oxidation by-products) via retention time matching and spectral comparison. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify volatile solvents (e.g., methanol, toluene, dichloromethane) per ICH Q3C guidelines. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (Pb, Cd, Hg, As) after acid digestion, offering sub-ppq detection sensitivity. |
| Moisture Content | Karl Fischer Titration | Volumetric or coulometric titration measuring water content via iodine–sulfur dioxide redox reaction in anhydrous pyridine/methanol medium. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid–liquid phase transition temperature using calibrated capillary apparatus per USP <741>. |
| Appearance & Color | Visual Inspection / APHA Color Scale | Assessment of physical state (crystalline solid) and color intensity against platinum-cobalt standards. |
| Sulfur Content | Oxidative Combustion followed by IC | High-temperature combustion converts organic sulfur to sulfate, quantified via ion chromatography with conductivity detection. |
| Chloride Impurity | Ion Chromatography (IC) or Potentiometric Titration | Quantification of chloride ions either by suppressed IC with conductivity detection or argentometric titration using AgNO₃. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a saturated aqueous suspension (1:10 w/v) to assess acidic/basic degradation products. |
| Specific Optical Rotation | Polarimetry | Determination of chiral purity (if applicable); though 4-nitroanisole derivative is achiral, rotation confirms absence of chiral contaminants. |
| Residue on Ignition | Gravimetric Analysis | Weighing non-volatile inorganic residue after high-temperature ashing (700–800 °C) per USP <281>. |
Technical Specifications of 4-NITROTHIOANISOLE
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 63–67°C |
| Identification (NMR) | Conforms to reference spectrum |
| Identification (IR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-NITROTHIOANISOLE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-NITROTHIOANISOLE
Packaging of 4-NITROTHIOANISOLE
Industrial 4-NITROTHIOANISOLE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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