6-Chloro-4-hydroxy-2-methyl-2H-thieno[2,3-e]-1,2-thiazine-3-carboxylic acid methyl ester 1,1-dioxide Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 70415-50-8 |
| Product name | 6-Chloro-4-hydroxy-2-methyl-2H-thieno[2,3-e]-1,2-thiazine-3-carboxylic acid methyl ester 1,1-dioxide |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 70415-50-8
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 70415-50-8 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 70415-50-8
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Serves as a key pharmaceutical intermediate for synthesizing the nonsteroidal anti-inflammatory drug (NSAID) piroxicam and its derivatives. | Used as a starting material in a condensation (amide formation) reaction with 2-aminopyridine, followed by downstream processing to yield the final active pharmaceutical ingredient. |
| Chemical Synthesis | Serves as a starting material or precursor for synthesizing thiazine derivatives. | Converted into other biologically active compounds via chemical modifications such as reduction, hydrolysis, or functional group transformation. |
| Research Reagents | Used in medicinal chemistry research and new drug screening. | Employed under laboratory conditions as a reference standard or reaction substrate for small-scale synthesis and structural confirmation. |
Manufacturing Quality Control of 70415-50-8
| Test Item | Common Test Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color, state, and presence of clumping or visible foreign matter under natural light or standard light sources. Suitable for preliminary assessment of solid active pharmaceutical ingredients. |
| Identification | Infrared Spectroscopy (IR) | Compare the characteristic absorption peaks (such as S=O, C=O, O-H, etc.) of the sample and reference standard under the same conditions to confirm the molecular structure. |
| Identification | HPLC (High-Performance Liquid Chromatography) | Compare the retention time of the sample with that of the reference substance to verify consistency of the main peak, used for auxiliary structural confirmation. |
| Content Determination | HPLC (High-Performance Liquid Chromatography) | Use a reverse-phase C18 column with water-organic solvent (such as methanol or acetonitrile) as the mobile phase, detect using a UV detector (e.g., 254 nm), and calculate the main component content by external standard method. |
| Related Substances (Impurities) | HPLC (High-Performance Liquid Chromatography) | Separate the main component and individual impurities using gradient or isocratic elution, and calculate the total impurity content and individual impurity limits by area normalization or self-comparison method. |
| Residual Solvents | Gas Chromatography (GC) | Detect residual organic solvents (such as methanol, ethanol, acetone, dichloromethane, etc.) according to ICH guidelines, using headspace sampling combined with FID detector for quantitative analysis. |
| Moisture | Karl Fischer Titration | Determine moisture content in the compound by titrating with Karl Fischer reagent, which includes volumetric or coulometric methods. |
| Melting Point | Capillary Melting Point Method | Pack the sample into a capillary tube and heat it in a melting point apparatus to record the initial and final melting temperatures, used to assess purity and material properties. |
| Heavy Metals | Thioacetamide Method (Chinese Pharmacopoeia Method) | Under acidic conditions, heavy metals react with thioacetamide to form colored sulfides; determine total heavy metal content (as lead) by colorimetry. |
| Drying Loss | Thermogravimetric Analysis (TGA) or Oven Drying Method | Dry the sample at a specified temperature (e.g., 105°C) until constant weight is achieved; calculate the volatile matter content based on weight loss. |
| Residue on Ignition | Sulfuric Acid Ignition Method | Treat the sample with sulfuric acid and then heat it to high temperature, weighing the remaining inorganic matter to assess the level of inorganic impurities. |
| Crystalline Form Analysis | X-ray Powder Diffraction (XRPD) | Analyze the characteristic diffraction peaks of the sample and compare them with standard crystalline pattern to control polymorphic forms. |
| Particle Size Distribution | Laser Diffraction Analysis (LDI) | Determine particle size and distribution using the principle of laser scattering, affecting solubility and formulation performance. |
Technical Specifications of 70415-50-8
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 212–216 °C |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 70415-50-8
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| Lot/Batch Number | *Required fields | |
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Industrial 70415-50-8 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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