China Factory Direct
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| CAS number | 7048-38-6 |
| Product name | (5-CHLORO-2-METHOXYPHENYL)ACETONITRILE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticides | Key intermediate in the synthesis of the insecticide flupyradifurone | Used to construct neonicotinoid structures via nitration, reduction, diazotization, and cyanation, followed by coupling with substrates such as 2-chloro-5-fluorobenzaldehyde |
| Pharmaceuticals | Structural motif in anticancer drug candidates and protein kinase inhibitors | Applied in Suzuki coupling or Pd-catalyzed C–H activation reactions to introduce the chloromethoxyphenylacetonitrile pharmacophore |
| Fine Chemicals | Functional building block for liquid crystal materials and organic optoelectronic materials | After hydrolysis, amidation, or reduction to the corresponding amine, incorporated into polymerization or molecular self-assembly to modulate dielectric anisotropy and charge-carrier mobility |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detector | Quantitative determination based on peak area comparison against a certified reference standard using a calibrated column and temperature program. |
| Related Substances | High Performance Liquid Chromatography (HPLC) with UV detection | Separation and quantification of structurally related impurities using reversed-phase C18 column and gradient elution with UV absorbance detection. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) with FID | Volatile organic solvents are equilibrated in headspace vial, injected into GC column, and quantified via external calibration curves. |
| Water Content | Karl Fischer Titration (Coulometric mode) | Electrochemical titration where iodine generated coulometrically reacts stoichiometrically with water; endpoint detected by dual-platinum electrode system. |
| Chloride Ion Impurity | Ion Chromatography (IC) with conductivity detection | Anionic impurities including chloride are separated on anion-exchange column and detected by suppressed conductivity measurement. |
| Heavy Metals (Pb, Cd, Hg, As) | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Multi-element trace metal quantification after acid digestion, based on element-specific mass-to-charge ratio detection with high sensitivity. |
| Acid Value | Acid-Base Titration with NaOH standard solution | Neutralization of acidic impurities (e.g., hydrolyzed nitrile or residual HCl) using standardized sodium hydroxide solution and potentiometric endpoint detection. |
| Appearance | Visual Inspection in Nessler Cylinder | Assessment of physical state, color, and clarity against water-white standard under controlled white light and specified viewing conditions. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid phase transition temperature range using calibrated digital melting point instrument per USP <741>. |
| Residue on Ignition | Gravimetric Analysis after Muffle Furnace Incineration | Non-volatile inorganic residue measured as weight percent after charring and ashing at 700-750 C in platinum crucible. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light caused by chiral impurities or enantiomeric excess, using sodium D-line at specified concentration and path length. |
| Particle Size Distribution | Laser Diffraction Particle Size Analysis | Size distribution determined from angular scattering pattern of laser beam passing through dispersed sample suspension in liquid medium. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 62–66°C |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.