China Factory Direct
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| CAS number | 704879-64-1 |
| Product name | benzyl piperidine-4-carboxylate;hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemistry | Used as a pharmaceutical intermediate for synthesizing bioactive molecules containing the piperidine moiety (e.g., antiviral, antitumor, or central nervous system agents) | Introduces the benzyloxycarbonyl-protected piperidine carboxylic acid unit via esterification, deprotection, or coupling reactions |
| Organic Synthesis | Serves as a key building block for constructing complex nitrogen-containing heterocycles | Participates in condensation or functional group transformations as a protected piperidine-4-carboxylic acid derivative in multistep syntheses |
| Drug Discovery | Employed to prepare candidate compound libraries for screening bioactive small molecules | Undergoes structural modification via combinatorial or parallel synthesis, using this compound as the starting material |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Piperidine-4-carboxylic acid benzyl ester hydrochloride) | HPLC-UV | Quantification by reversed-phase HPLC with UV detection at 210 nm, using external standard calibration. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC with UV detection; identification based on retention time matching and relative response factors. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, ethyl acetate, toluene) against calibrated standards. |
| Water Content | Karl Fischer Titration | Electrochemical titration with iodine-based reagent to determine trace water content based on stoichiometric reaction. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using a silver indicator electrode to determine chloride ion concentration in aqueous solution. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and Ni after acid digestion, using plasma excitation and optical emission detection. |
| Residue on Ignition | Gravimetric Analysis | Measurement of non-volatile inorganic residue after high-temperature incineration at 700-800 C. |
| Optical Rotation | [alpha]D Measurement | Determination of specific rotation using a polarimeter at 20 C with sodium D-line (589 nm) light source. |
| Melting Point | Capillary Melting Point Apparatus | Thermal determination of solid-to-liquid transition range using controlled heating and visual observation. |
| pH of Aqueous Solution | pH Meter | Measurement of hydrogen ion activity in a 1% w/v aqueous suspension using calibrated glass electrode. |
| Particle Size Distribution | Laser Diffraction | Analysis of particle size distribution in dispersed powder sample using Mie scattering theory and laser diffraction. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic microorganisms and detection of specified pathogens (e.g., E. coli, S. aureus) by filtration and culture on selective media. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 162°C - 167°C |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.