China Factory Direct
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| CAS number | 705-09-9 |
| Product name | 2-Difluoromethyl-1H-benzoimidazole |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a pharmaceutical intermediate for synthesizing antifungal or antiviral active compounds | Introducing the difluoromethyl group via fluorination of benzimidazole derivatives |
| Agrochemicals | Used in developing novel agrochemical intermediates with potential insecticidal or fungicidal activity | Introducing the difluoromethyl group onto the benzimidazole ring via electrophilic fluorination or fluoroalkylation |
| Polymers & Materials | Used as a functional monomer or additive to enhance thermal stability and chemical inertness of materials | Incorporating 2-difluoromethyl-1H-benzimidazole into polymer chains via polymerization |
| Organic Synthesis | Used as a versatile reagent in organic synthesis, participating in coupling or substitution reactions | Performing C–H fluoroalkylation or cross-coupling reactions under palladium catalysis |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-DAD | Separation and identification of impurities using HPLC coupled with diode-array detection; relative retention times and spectral matching support qualification. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common organic solvents based on calibrated external standards. |
| Water Content | Karl Fischer Titration | Volumetric titration using iodine, sulfur dioxide, and pyridine in methanol; water reacts stoichiometrically to determine trace moisture. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, using isotopic mass spectrometry for sub-ppq sensitivity. |
| Chloride Impurity | Ion Chromatography | Separation of anions on anion-exchange column with conductivity detection; chloride is quantified against calibration standards. |
| Sulfated Ash | Gravimetric Analysis | Sample ignited at 700-800 C after sulfuric acid treatment; residual inorganic ash is weighed to assess inorganic residue content. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually or automatically as the solid-to-liquid phase change under controlled heating rate. |
| Loss on Drying | Thermogravimetric Analysis (TGA) | Mass loss measured gravimetrically upon heating to 105 C under nitrogen, indicating volatile content including residual solvents and moisture. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity to calculate volume-based particle size distribution in dispersed powder samples. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through a solution, indicating chiral purity and identity confirmation. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | pH electrode measurement of saturated aqueous suspension to assess acidic/basic impurity profile and stability indicators. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 148–152°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.