7-Hydroxyquinolinone Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 70500-72-0 |
| Product name | 7-Hydroxyquinolinone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 7-Hydroxyquinolinone
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 7-Hydroxyquinolinone Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 7-Hydroxyquinolinone
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Intermediate in drug synthesis | Serves as a key structural unit in constructing the quinolone core structure of antibiotics (e.g., fleroxacin) and their derivatives via N-alkylation, condensation, or substitution reactions. |
| Pharmaceutical Industry | Synthesis of central nervous system (CNS) drugs | Used to synthesize biologically active quinolone derivatives as intermediates for preparing GABA receptor antagonists or nootropic agents. |
| Agrochemical Industry | Intermediate for fungicides | Applied in synthesizing quinolone-based agricultural fungicides, participating in synthetic reactions to introduce specific pharmacophores. |
| Organic Synthesis | Synthesis of functional dyes and intermediates | Leverages its conjugated molecular system; chemically modified to serve as an intermediate raw material for synthesizing organic pigments or functional dyes. |
| Research Field | Biological activity screening | Serves as a candidate compound or lead compound in antimicrobial and antitumor activity assays, as well as in structure–activity relationship (SAR) studies. |
Manufacturing Quality Control of 7-Hydroxyquinolinone
| Test Item | Common Test Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical state, and presence of visible impurities under natural or standard lighting conditions. |
| Melting Point | Capillary Melting Point Method | Determine the initial and final melting temperatures using a melting point apparatus to assess purity and substance consistency. |
| Assay | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with methanol-water or acetonitrile-water as the mobile phase. Detect analytes using a UV detector (typically at 254 nm or 310 nm) and quantify the main component via external or internal standard methods. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Similar to assay determination, but employs gradient elution for better separation of impurity peaks. Impurity levels are evaluated using peak area normalization or reference standard (external standard) methods. |
| Solubility | Solubility Test | Add the sample to various solvents (e.g., water, ethanol, methanol, DMSO), shake, and observe dissolution behavior to qualitatively assess solubility. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Oven Drying Method | Dry the sample at a specified temperature (e.g., 105°C) until constant weight is achieved. Calculate the percentage weight loss to evaluate moisture and volatile impurity content. |
| Sulfated Ash (Residue on Ignition) | Gravimetric Method | Treat the sample with sulfuric acid, then incinerate at high temperature. Weigh the residual inorganic matter to determine inorganic impurity content. |
| Heavy Metals | Thioacetamide Method (Chinese Pharmacopoeia) | In mildly acidic conditions, heavy metals react with thioacetamide to form colored sulfide precipitates. Quantify by color comparison, usually calculated as lead equivalents. |
| Water Content | Karl Fischer Titration (KF Method) | Utilize the quantitative reaction of iodine, sulfur dioxide, and water in a pyridine/methanol system to determine water content; suitable for trace moisture analysis. |
| Structural Confirmation | Fourier Transform Infrared Spectroscopy (FT-IR) | Obtain the infrared absorption spectrum of the sample and compare it with reference spectra to confirm the presence of functional groups (e.g., hydroxyl, carbonyl, aromatic rings). |
| Nuclear Magnetic Resonance Spectroscopy (NMR) | Analyze chemical environments of hydrogen and carbon atoms using ¹H-NMR and ¹³C-NMR to confirm molecular structure. | |
| Mass Spectrometry (MS) | Obtain molecular ion peaks and fragmentation patterns using ionization methods such as ESI or EI to verify molecular weight and structural fragments. |
Technical Specifications of 7-Hydroxyquinolinone
| Test Item | Specification |
|---|---|
| Appearance | Off-white solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 178–182°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 7-Hydroxyquinolinone
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 7-Hydroxyquinolinone
Packaging of 7-Hydroxyquinolinone
Industrial 7-Hydroxyquinolinone Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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