China Factory Direct
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| CAS number | 705280-65-5 |
| Product name | 1H-Imidazole-4,5-dicarboxylic acid, 2-bromo-, 4,5-dimethyl ester |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of imidazole-based drug intermediates | Introduces specific functional groups via bromination, esterification, and related reactions |
| Agrochemicals | Preparation of nitrogen-containing heterocyclic agrochemical precursors | Constructs active molecular frameworks through cyclization and substitution reactions |
| Materials Science | Synthetic building block for functional organic materials | Used in polymerization or structural modification to tailor material properties |
| Organic Synthesis | Key intermediate for constructing complex organic molecules | Participates in multi-step synthetic reactions, including coupling and cycloaddition |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at ~220–254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV or UPLC-UV | Separation and detection of structurally related impurities (e.g., mono-brominated, hydrolyzed, or unreacted intermediates) using gradient elution and UV detection. |
| Residual Solvents | GC-FID or GC-MS | Headspace gas chromatography with flame ionization detection (or mass spectrometry) to quantify residual solvents (e.g., methanol, DMF, dichloromethane) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration quantifying water via iodine generation and stoichiometric reaction with water in anhydrous medium. |
| Heavy Metals | ICP-MS or ICP-OES | Quantitative determination of elemental impurities (e.g., Pd, Cu, Fe, Ni) after acid digestion, per ICH Q3D requirements. |
| Residual Palladium | ICP-MS | Ultra-trace quantification of palladium (common catalyst residue) using isotope-dilution or external calibration in digested sample solution. |
| Chloride Impurity | Ion Chromatography (IC) or Potentiometric Titration | Separation and detection of chloride ions via suppressed conductivity detection (IC), or direct titration with silver nitrate. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement using calibrated capillary apparatus; indicative of crystallinity and presence of impurities. |
| Appearance | Visual Inspection | Assessment of physical state (crystalline powder), color (white to off-white), and absence of visible particulates or discoloration under controlled lighting. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light in solution; used to confirm chiral integrity (though compound is achiral, detects chiral contaminants). |
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (HPLC) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.