1-CBZ-2-PIPERIDINECARBOXYLIC ACID Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 71170-88-2 |
| Product name | 1-CBZ-2-PIPERIDINECARBOXYLIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1-CBZ-2-PIPERIDINECARBOXYLIC ACID
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-CBZ-2-PIPERIDINECARBOXYLIC ACID Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-CBZ-2-PIPERIDINECARBOXYLIC ACID
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of pharmaceutical intermediates | Prepared by reacting N-Cbz-protected amino acids with corresponding piperidines |
| Medicine | Raw material for drug synthesis | Used in the synthesis of biologically active compounds, such as antidepressants and anticancer agents |
Manufacturing Quality Control of 1-CBZ-2-PIPERIDINECARBOXYLIC ACID
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at ~210 nm, comparing peak area to a certified reference standard. |
| Chiral Purity | Chiral HPLC | Enantiomeric separation on a chiral stationary phase, with UV detection to determine enantiomeric excess (ee). |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, ethyl acetate, toluene) against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to selectively determine trace water content. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion and matrix-matched calibration. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and conductivity detection of chloride ions in aqueous extract; quantified against chloride standard. |
| Related Substances | HPLC-UV (Forced Degradation Study) | HPLC method validated for specificity, detecting structurally related impurities (e.g., N-CBZ-piperidine, hydrolysis/degradation products). |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid transition temperature range using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against defined reference standards under controlled lighting. |
| Residue on Ignition | Gravimetric Analysis | Weighing residue remaining after high-temperature ashing (700–800 °C) to assess inorganic impurities. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light at specified wavelength (e.g., 589 nm) and concentration to confirm chiral identity and purity. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersion using Mie theory to determine D10, D50, D90 values per ISO 13320. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode per USP <791>. |
Technical Specifications of 1-CBZ-2-PIPERIDINECARBOXYLIC ACID
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78-82°C |
| Identification (NMR) | Consistent with structure |
| Optical Rotation | [α]²⁰D = -15.0° to -19.0° (c=1, in methanol) |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1-CBZ-2-PIPERIDINECARBOXYLIC ACID
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Safety Information of 1-CBZ-2-PIPERIDINECARBOXYLIC ACID
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 1-CBZ-2-PIPERIDINECARBOXYLIC ACID
Industrial 1-CBZ-2-PIPERIDINECARBOXYLIC ACID Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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