2-METHOXY-3-PYRIDINECARBOXALDEHYDE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 71255-09-9 |
| Product name | 2-METHOXY-3-PYRIDINECARBOXALDEHYDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-METHOXY-3-PYRIDINECARBOXALDEHYDE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-METHOXY-3-PYRIDINECARBOXALDEHYDE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-METHOXY-3-PYRIDINECARBOXALDEHYDE
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of the antitumor drug ibrutinib | Used to prepare ibrutinib via multi-step reactions including Pd-catalyzed cross-coupling with 4-bromoaniline and subsequent cyclization |
| Agrochemicals | Intermediate for novel neonicotinoid insecticides (e.g., structurally analogous neonicotinoid derivatives) | Applied in reductive amination, chlorination, and subsequent heterocycle construction to optimize insecticidal activity |
| Organic Synthesis | Multifunctional heterocyclic aldehyde reagent for constructing pyridine-containing ligands or functional molecules | Commonly employed in Wittig reactions, Knoevenagel condensations, reductive aminations, and metal-catalyzed C–H activation coupling reactions |
Manufacturing Quality Control of 2-METHOXY-3-PYRIDINECARBOXALDEHYDE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at ~254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities (e.g., unreacted 2-methoxypyridine, oxidation/by-product peaks) relative to main peak using validated gradient HPLC. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify common solvents (e.g., methanol, dichloromethane, toluene) based on retention time and calibration curves. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine generation in pyridine-free reagent; water reacts stoichiometrically with iodine and sulfur dioxide in methanol medium. |
| Heavy Metals (as Pb) | ICP-OES | Multi-element quantification after acid digestion; detection based on characteristic atomic emission lines following plasma excitation. |
| Chloride Impurity | Ion Chromatography | Separation of chloride anions on an anion-exchange column with suppressed conductivity detection; quantified against sodium chloride standard. |
| Sulfated Ash | Gravimetric Analysis | Ignition of sample at 700-800 C followed by sulfuric acid treatment and final weighing of non-volatile residue. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually or automatically as the temperature range over which solid transforms to liquid. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity of neat substance under controlled white light against established visual standards. |
| Odor | Olfactory Assessment | Qualified personnel evaluate characteristic pungent aldehyde odor; deviation indicates degradation or contamination. |
| Acidity (as Acetic Acid) | Acid-Base Titration | Titration with standardized sodium hydroxide solution using phenolphthalein indicator; measures acidic impurities that consume base. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through a solution; confirms chiral purity if applicable (though compound is achiral, used for consistency). |
Technical Specifications of 2-METHOXY-3-PYRIDINECARBOXALDEHYDE
| Test Item | Specification |
|---|---|
| Appearance | Colorless liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Refractive Index (n20/D) | 1.535–1.545 |
| Odor | Characteristic odor |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-METHOXY-3-PYRIDINECARBOXALDEHYDE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-METHOXY-3-PYRIDINECARBOXALDEHYDE
Safety Information of 2-METHOXY-3-PYRIDINECARBOXALDEHYDE
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 2-METHOXY-3-PYRIDINECARBOXALDEHYDE
Industrial 2-METHOXY-3-PYRIDINECARBOXALDEHYDE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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