Methyl D-valinate hydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 7146-15-8 |
| Product name | Methyl D-valinate hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Methyl D-valinate hydrochloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Methyl D-valinate hydrochloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Methyl D-valinate hydrochloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral building block for synthesis of antiviral agents and protease inhibitors | Prepared via esterification of D-valine with methanol under hydrochloric acid catalysis |
| Pharmaceuticals | Amino acid derivative intermediate for synthesis of non-natural amino acid-based drugs | Reaction of D-valine with thionyl chloride and methanol at low temperature, followed by hydrochloride salt formation and purification |
| Chemical Synthesis | Chiral auxiliary or ligand precursor for asymmetric catalytic reactions | Introduction of chiral valine residues via solid-phase or solution-phase peptide synthesis, followed by methyl esterification and hydrochloride salt formation |
Manufacturing Quality Control of Methyl D-valinate hydrochloride
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (D-Valine Methyl Ester HCl) | Acid-Base Titration | Quantifies active compound by titration with standardized NaOH using phenolphthalein indicator; accounts for HCl salt content. |
| Enantiomeric Purity | Chiral HPLC | Separates D- and L-enantiomers on a chiral stationary phase; detection via UV absorbance at 210 nm. |
| Water Content | Karl Fischer Titration | Measures trace water by coulometric or volumetric reaction with iodine, sulfur dioxide, and base in methanol. |
| Residual Solvents | Gas Chromatography (GC-FID) | Quantifies volatile organic solvents (e.g., methanol, dichloromethane) using flame ionization detection. |
| Heavy Metals | ICP-OES | Determines total elemental impurities (Pb, Cd, Hg, As, etc.) by plasma excitation and optical emission spectroscopy. |
| Chloride Impurity | Potentiometric Titration | Titrates Cl- with AgNO3 using silver indicator electrode; endpoint detected by potential inflection. |
| Related Substances | Reverse-Phase HPLC | Separates and quantifies structurally related impurities (e.g., D-valine, methyl ester hydrolysis products) using C18 column and UV detection. |
| pH of Aqueous Solution | pH Meter Measurement | Measures hydrogen ion activity in a 1% w/v aqueous solution using calibrated glass electrode. |
| Loss on Drying | Gravimetric Analysis | Determines volatile matter by weight loss after drying at 105 C under vacuum for 2 hours. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles against standard white background under controlled lighting. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary tube method. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light at 589 nm to confirm chiral integrity and concentration-dependent specific rotation. |
Technical Specifications of Methyl D-valinate hydrochloride
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148~152°C |
| Optical Rotation | -13.5 to -17.5° (c=1, in 6N HCl) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Methyl D-valinate hydrochloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Methyl D-valinate hydrochloride
Safety Information of Methyl D-valinate hydrochloride
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Methyl D-valinate hydrochloride
Industrial Methyl D-valinate hydrochloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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