Isoquinoline-4-carboxylic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 7159-36-6 |
| Product name | Isoquinoline-4-carboxylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Isoquinoline-4-carboxylic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Isoquinoline-4-carboxylic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Isoquinoline-4-carboxylic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Pharmaceutical Intermediates | Serves as a key building block in the synthesis of protein kinase inhibitors (e.g., ROCK inhibitors, p38 MAPK inhibitors) and participates in constructing the isoquinoline scaffold of drug molecules. |
| Pharmaceutical Chemicals | Active Pharmaceutical Ingredient (API) Synthesis | Used in the synthesis of potential antitumor, anti-inflammatory, and antithrombotic agents via carboxyl–amine condensation to introduce the isoquinoline moiety. |
| Biochemistry | Inhibitor Research | Employed as a substrate or inhibitor analog in enzyme activity assays and inhibitor screening studies. |
| Organic Synthesis | Ligand Synthesis | Utilizes its carboxylic acid group to prepare nitrogen-containing heterocyclic carboxylic acid ligands for constructing metal–organic frameworks (MOFs) or metal-catalyzed complexes. |
| Agrochemicals | Agrochemical Intermediates | Applied in synthesizing bioactive molecules containing the isoquinoline structure for developing novel agrochemicals. |
Manufacturing Quality Control of Isoquinoline-4-carboxylic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination based on peak area comparison with a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of structurally similar impurities using gradient reversed-phase HPLC with UV detection. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents by gas chromatography with flame ionization detection using headspace sampling. |
| Heavy Metals | ICP-OES | Multi-element determination of metallic impurities (e.g., Pb, Cd, Ni, Fe) after acid digestion, based on atomic emission intensity. |
| Chloride Content | Ion Chromatography | Quantification of chloride ions via suppressed conductivity detection after anion exchange separation. |
| Sulfate Content | Ion Chromatography | Quantification of sulfate ions via suppressed conductivity detection after anion exchange separation. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration measuring water content based on the stoichiometric reaction of iodine with water in pyridine-methanol medium. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid-to-liquid phase transition occurs, using calibrated capillary method per USP <741>. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles under controlled white light against standard references. |
| Loss on Drying | Gravimetric Method | Measurement of mass loss after drying under specified temperature and vacuum conditions to determine volatile matter content. |
| Residue on Ignition | Gravimetric Method | Determination of non-volatile inorganic residue after high-temperature ashing in a muffle furnace. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light caused by chiral molecules in solution, using sodium D-line at 20 C. |
Technical Specifications of Isoquinoline-4-carboxylic acid
| Test Item | Specification |
|---|---|
| Appearance | Off-white solid |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 178–182°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Isoquinoline-4-carboxylic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Isoquinoline-4-carboxylic acid
Safety Information of Isoquinoline-4-carboxylic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Isoquinoline-4-carboxylic acid
Industrial Isoquinoline-4-carboxylic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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