China Factory Direct
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| CAS number | 71666-95-0 |
| Product name | H-HIS-NH2 2HCL |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent GradeFood Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Biopharmaceuticals | Used in the synthesis of L-histidine-related pharmaceutical intermediates | Chemical synthesis: preparation of amide hydrochloride via reaction of histidine with hydrochloric acid |
| Nutritional fortification | Added as an amino acid nutritional supplement to functional foods or beverages | Purified via enzymatic or chemical methods, then formulated into food systems |
| Research reagents | Used as reference standards or reactants in biochemical research | High-purity refinement process suitable for laboratory analysis and testing |
| Medical diagnostics | Component of reagents for detection of specific metabolic disorders | Quantitative analysis performed in conjunction with enzyme-linked immunosorbent assay (ELISA) or mass spectrometry |
| Biotechnology | Supplied as a medium component to support cell growth and protein expression | Added to cell culture media to maintain amino acid balance |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Acid-Base Titration | Quantifies L-histidine amide hydrochloride by titration with standardized NaOH using an appropriate indicator or potentiometric endpoint. |
| Water Content | Karl Fischer Titration | Measures water content via coulometric or volumetric reaction between water and iodine in a methanol-based reagent. |
| Residual Solvents | Gas Chromatography (GC) | Separates and quantifies volatile organic solvents (e.g., methanol, ethyl acetate) using a flame ionization detector. |
| Heavy Metals | ICP-OES | Determines total heavy metal content (e.g., Pb, Cd, Hg, As) by plasma excitation and elemental emission spectroscopy. |
| Chloride Content | Potentiometric Titration | Measures chloride ions using silver nitrate titrant and a silver/silver chloride electrode for endpoint detection. |
| Specific Optical Rotation | Polarimetry | Evaluates enantiomeric purity by measuring the angle of rotation of plane-polarized light in solution. |
| pH (1% aqueous solution) | pH Meter Measurement | Determines acidity/basicity of a 1% w/v aqueous solution using calibrated pH electrode. |
| Related Substances | High Performance Liquid Chromatography (HPLC) | Separates and quantifies structurally related impurities using reversed-phase C18 column and UV detection. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic ash content after high-temperature incineration and weighing of residual material. |
| Microbial Contamination | Membrane Filtration | Detects aerobic microorganisms by filtration, membrane transfer to culture medium, and colony enumeration. |
| Particle Size Distribution | Laser Diffraction | Determines particle size distribution by analyzing angular scattering pattern of laser light passed through dispersed sample. |
| Melting Point | Capillary Melting Point Apparatus | Identifies melting range by observing solid-to-liquid transition under controlled heating rate. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 245-249°C (decomposes) |
| Optical Rotation | +21.0 to +23.0° (c=1, H2O) |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.