China Factory Direct
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| CAS number | 719-59-5 |
| Product name | 2-Amino-5-chlorobenzophenone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for synthesizing antidepressants, antipsychotics, and other benzophenone-based drugs | Used as a key intermediate in drug molecule construction via nucleophilic substitution, reduction, or coupling reactions |
| Pesticides | Intermediate for synthesizing chlorinated benzophenone-based fungicides or insecticides | Applied in introducing active structural units through halogenated aryl coupling, acylation, or cyclization reactions |
| Dyes & Pigments | Photosensitizer or dye intermediate for synthesizing specialized UV-absorbing dyes | Used in preparing functionalized dye molecules via condensation, sulfonation, or diazotization reactions |
| Milestone | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance and Physical Properties | Visual Inspection + Physical Property Measurement | Observe the sample's color and state (typically a white to pale yellow crystalline powder), determine the melting point (literature value approximately 135–140°C), and ensure it meets pharmacopoeia or internal control standards. |
| Content Determination (Main Component) | High-Performance Liquid Chromatography (HPLC) | Use a C18 chromatographic column, with a mobile phase of methanol-water or acetonitrile-phosphate buffer solution, detected by UV detector (UV 254 nm or 280 nm), and quantified by external standard method, ensuring the main component content ≥98.0%. |
| Impurity Profile Analysis | High-Performance Liquid Chromatography (HPLC) | Use gradient elution to detect process impurities (such as unreacted raw materials, dechlorination by-products, oxidation products, etc.), set impurity limits (e.g., single impurity ≤0.1%, total impurities ≤0.5%). |
| Chlorine Content | Combustion Ion Chromatography (CIC) or Oxygen Bomb Combustion + Ion Chromatography | The sample is combusted in an oxygen bomb and absorbed into alkaline solution, converted into chloride ions, then determined by ion chromatography. Compare with theoretical chlorine content (theoretical value approximately 27.5%) to confirm structural integrity. |
| Moisture Content | Karl Fischer Titration Method | Quantitatively react water with iodine-sulfur dioxide-pyridine-methanol system, determine trace moisture in the sample, control moisture ≤0.5% to avoid hydrolysis or storage instability. |
| Solvent Residues | Gas Chromatography (GC) | Use headspace injection or direct injection, with DB-624 or HP-INNOWAX column, detect residual solvents (such as methanol, ethanol, ethyl acetate, DMF), conforming to ICH Q3C limits. |
| Melting Point | Capillary Melting Point Apparatus | Precisely measure the melting point range of the sample, compare with standard or literature values (approximately 135–140°C), used for preliminary identification and purity assessment. |
| UV-Vis Absorption Spectra | UV-Vis Spectrophotometry | Dissolve the sample in methanol or ethanol, measure absorption spectra in the wavelength range of 200–400 nm, characteristic absorption peaks (e.g., λmax ≈ 285 nm) are used for qualitative confirmation. |
| Heavy Metal Residues | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After wet digestion, determine the content of heavy metals such as lead, cadmium, mercury, and arsenic, conforming to pharmacopoeia limits (e.g., Pb ≤5 ppm). |
| Residual Chloride Ions | Silver Nitrate Titration or Ion Chromatography | Dissolve the sample, acidify with nitric acid, and titrate with silver nitrate or detect chloride ions by ion chromatography, controlling no excess inorganic chloride residues. |
| Polymorphic Analysis (Optional) | X-ray Powder Diffraction (XRPD) | Used to confirm the presence of polymorphs, ensuring consistent physical properties between batches, suitable for quality control of high-purity active pharmaceutical ingredients. |
| Test Item | Specification |
|---|---|
| Appearance | Light yellow to green crystalline powder |
| Purity | >=98.5% (by LC-MS) |
| Melting Point | 128–132°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.