China Factory Direct
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| CAS number | 71989-28-1 |
| Product name | FMOC-L-Methionine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Monomer for synthesizing peptide-based drugs | Used as a protected amino acid in solid-phase or solution-phase peptide synthesis |
| Medical Devices | Preparation of bioactive peptides | Applied in Fmoc-based peptide synthesis for stepwise amino acid coupling |
| Research & Development | Reference standard or reagent | Employed as a starting material or control substance in peptide synthesis research |
| Biotechnology | Development of diagnostic reagents | Used to synthesize sequence-specific recognition fragments via peptide sequence design |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 268 nm, comparing peak area against a certified reference standard. |
| Chiral Purity | Chiral HPLC | Separation of enantiomers on a chiral stationary phase; L-isomer content calculated from peak area ratio relative to D-isomer and racemate standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration based on the stoichiometric reaction of iodine with water in a pyridine-methanol buffer system. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify common solvents (e.g., DMF, dichloromethane) using external calibration. |
| Heavy Metals | ICP-MS | Multi-element quantification of Pb, Cd, Hg, As, and others after acid digestion, using isotopic dilution or external calibration for trace-level sensitivity. |
| Specific Optical Rotation | [alpha]D | Measurement of plane-polarized light rotation in solution at 20 C using sodium D-line (589 nm); confirms identity and enantiomeric integrity. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles under controlled lighting against established reference standards. |
| pH (1% w/v aqueous solution) | pH Meter | Potentiometric measurement using calibrated pH electrode in a saturated aqueous suspension adjusted to 1% concentration. |
| Loss on Drying | Gravimetric Analysis | Weight loss measured after drying under specified conditions (e.g., 105 C, 2 h) to determine volatile content including residual moisture and solvents. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., Fmoc-Met sulfoxide, deprotected Met, dipeptides) using gradient HPLC with UV detection. |
| Residual Palladium | ICP-OES | Quantification of Pd catalyst residues after microwave-assisted acid digestion, using axial-view ICP-OES with matrix-matched calibration. |
| Microbial Contamination | Membrane Filtration | Enumeration of aerobic microorganisms and absence of specified pathogens (e.g., E. coli, S. aureus) per pharmacopeial methods (USP <61>, <62>). |
| Test Item | Specification |
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| Appearance | Off-white solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | -32.0 to -27.0 deg (c=1, in DMF) |
| Melting Point | 148 to 152 °C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.