China Factory Direct
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| CAS number | 71989-38-3 |
| Product name | Fmoc-Tyr(tBu)-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of peptide-based drugs | Monomer feedstock in solid-phase or solution-phase peptide synthesis |
| In Vitro Diagnostics | Intermediate in the synthesis of labeling agents | Participates in the construction of labeled compounds after introduction of protecting groups |
| Biotechnology | Research and development of bioactive molecules | Introduces specific functional groups into peptide sequences |
| Chemical Reagents | Building block for organic synthesis | Undergoes chemical transformations such as substitution and coupling reactions |
| Materials Science | Design of functional polymers | Provides biocompatible side-chain structural units |
| Test Item | Common Testing Methods | Method Summary |
|---|---|---|
| Appearance | Visual Inspection | Visually examine the sample for color, physical state (e.g., white to off-white crystalline powder), and presence of visible foreign matter to determine compliance with specifications. |
| Identification | Infrared Spectroscopy (IR) High-Performance Liquid Chromatography (HPLC) Proton Nuclear Magnetic Resonance (¹H NMR) |
IR: Compare the infrared absorption spectrum of the sample with that of a reference standard; HPLC: Confirm identity by matching retention time with reference standard; ¹H NMR: Verify characteristic chemical shift peaks (e.g., aromatic protons, tert-butyl signals) consistent with the theoretical molecular structure. |
| Purity / Related Substances | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with gradient elution employing acetonitrile-water or methanol-water as mobile phase. Determine purity by peak area normalization and identify/quantify potential impurities (e.g., deprotection by-products, oxidation products). |
| Specific Optical Rotation | Polarimetry | Measure the optical rotation of the sample solution at a specified wavelength (typically sodium D line, 589 nm) and temperature, then calculate the specific rotation to verify optical purity and configuration (L-isomer should exhibit a specific positive range). |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Atmospheric Drying Method | Dry the sample at a specified temperature (e.g., 105°C) until constant weight is achieved, then determine the percentage weight loss to assess moisture and volatile content. |
| Sulfated Ash / Residue on Ignition | High-Temperature Ashing Method | Ignite the sample at high temperature (typically 700–800°C), then weigh the residual inorganic matter to control inorganic impurities (e.g., metal catalyst residues). |
| Water Content | Karl Fischer Titration | Determine water content using volumetric or coulometric Karl Fischer titration to ensure compliance with storage and reaction stability requirements. |
| Residual Solvents | Gas Chromatography (GC) | Use headspace or direct injection GC to detect organic solvents potentially remaining from synthesis or purification (e.g., dichloromethane, DMF, ethanol), with limits controlled according to ICH Q3C guidelines. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Digest the sample and measure concentrations of heavy metal elements such as lead, cadmium, mercury, and arsenic to ensure compliance with pharmacopoeial or customer-specified limits. |
| Test Item | Specification |
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| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | -32.0 to -28.0 deg (c=1, in DMF) |
| Melting Point | 148 to 152 °C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.