China Factory Direct
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| CAS number | 72-40-2 |
| Product name | 4-Amino-5-imidazolecarboxamide hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Chemical synthesis intermediate | Serves as a key precursor in the synthesis of purine derivatives, including adenine, guanine, and their nucleoside analogues; enables introduction of imidazo[1,2-a]pyrrole structural motifs during molecular modification. |
| Pharmaceutical Chemicals | Antiviral and antitumor drug development | Used to synthesize biologically active heterocyclic compounds—e.g., as a building block for antimetabolite drugs (such as purine analogues)—in drug molecule construction and structural modification. |
| Biochemistry | Nucleic acid and nucleotide synthesis research | Applied in enzymatic or chemical synthesis studies to model purine metabolism pathways, synthesize isotopically labeled compounds, and investigate nucleotide metabolic mechanisms. |
| Organic Synthesis | Heterocycle construction | Enables construction of fused or heterocyclic systems—including imidazole and purine scaffolds—via cyclization, condensation, and other organic reactions leveraging its intramolecular amino and amide functional groups. |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Identity Test | Infrared Spectroscopy (IR) | Determine the infrared absorption spectrum of the sample and compare it with standard spectra to confirm functional groups and molecular structure characteristics. |
| Proton Nuclear Magnetic Resonance (¹H NMR) | Analyze hydrogen atoms using nuclear magnetic resonance technology, examining chemical shifts and coupling constants to verify compound structure. | |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Use a reverse-phase C18 column with a specific mobile phase (e.g., phosphate buffer-acetonitrile system) for separation, and quantify the main component using a UV detector (typically 210–260 nm). |
| Related Substances/Impurity Check | High-Performance Liquid Chromatography (HPLC) | Separate and detect potential process impurities or degradation products under similar conditions or gradient elution programs as in content determination, quantifying by area normalization or correction factor method. |
| Dry Loss | Thermogravimetric Analysis (TGA) or Constant-Temperature Drying Method | Dry the sample at a specified temperature (e.g., 105°C) until constant weight is achieved, then calculate the percentage of mass lost due to water or other volatile components. |
| Residual Solvents | Gas Chromatography (GC) | Use headspace or direct injection combined with an FID detector to determine residual organic solvents (e.g., methanol, ethanol, dichloromethane) from the production process. |
| Heavy Metals | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or Atomic Absorption Spectrometry (AAS) | Dissolve the sample and measure the residue levels of harmful elements such as lead, cadmium, mercury, and arsenic to ensure compliance with pharmacopoeia limits. |
| pH Value | pH Meter Measurement | Prepare a solution of a certain concentration (e.g., 1% w/v) in water and measure its acidity or alkalinity using a calibrated pH meter. |
| Specific Rotation (if applicable) | Polarimeter Method | If the compound contains a chiral center and optical purity needs to be controlled, measure its specific rotation and compare it with the standard value. |
| Appearance and Characteristics | Visual Inspection | Observe the color, crystal form, and odor of the sample. It should appear as a white to off-white crystalline powder with no unusual odor. |
| Chloride Content (as hydrochloride salt) | Ion Chromatography (IC) or Argentometric Titration | Determine Cl⁻ content to verify whether the hydrochloride salt conforms to the stoichiometric ratio, commonly using ion chromatography or titration methods. |
| Test Item | Specification |
|---|---|
| Appearance | Light-gray solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 245-249°C (decomposes) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.