China Factory Direct
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| CAS number | 7220-79-3 |
| Product name | Methylene Blue trihydrate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Antimalarial agent, antidote (e.g., for cyanide poisoning), treatment of methemoglobinemia | Administered via intravenous injection or oral dosing |
| Biological/Medical Research | Cell staining, histological staining, redox indicator | Microscopic observation, live-cell staining, electrochemical detection |
| Water Treatment | Tracer dye for monitoring water flow and leak detection | Injected into water systems and tracked colorimetrically |
| Textile Dyeing and Printing | Blue dye for cotton, silk, paper, and other substrates | Immersion dyeing or direct dyeing process |
| Analytical Chemistry | Redox indicator, reagent for photometric determination | Titrations, spectrophotometric analysis |
| Photodynamic Therapy | Photosensitizer for antimicrobial and antiviral applications | Generates reactive oxygen species upon irradiation at specific wavelengths |
| Educational Experiments | Demonstration of redox reactions, blue bottle experiment | Reversible color-change demonstration in alkaline glucose solution |
| Test Item | Common Testing Methods | Method Summary |
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| Appearance | Visual Inspection | Observe the color and physical state of the sample. Qualified methylene blue should appear as dark blue lustrous crystals or powder, free from visible impurities. |
| Identification | UV-Visible Spectrophotometry (UV-Vis) | Identification based on the characteristic absorption peak of methylene blue at a specific wavelength (e.g., around 664 nm). |
| Assay | Spectrophotometry / Titration | Spectrophotometry: Determine concentration by measuring absorbance at the maximum absorption wavelength according to the Lambert-Beer law. Titration: Redox titration (e.g., reaction with ascorbic acid or indirect determination via iodometric method). |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Use reversed-phase HPLC to separate the main component from impurities (such as intermediates or degradation products); impurity levels are evaluated using reference standards or area normalization methods. |
| Loss on Drying | Thermogravimetric Analysis (or Oven Method) | Dry the sample at 105°C to constant weight; calculate the content of moisture and volatile substances based on weight loss. |
| Sulfated Ash (Residue on Ignition) | Gravimetric Method | After high-temperature incineration of the sample, the residue is treated with sulfuric acid and weighed to assess inorganic impurity content. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After sample digestion, determine the content of heavy metal elements such as lead, mercury, and cadmium using AAS or inductively coupled plasma mass spectrometry (ICP-MS). |
| pH Value | pH Meter Method | Prepare an aqueous solution of specified concentration (e.g., 0.1%), then measure acidity or alkalinity using a calibrated pH meter. |
| Solubility | Solubility Test | Observe the solubility of methylene blue in solvents such as water, ethanol, and chloroform, confirming compliance with pharmacopoeial requirements. |
| Microbial Limits | Microbial Limit Test | Perform tests according to pharmacopoeial requirements, including total aerobic microbial count, mold and yeast count, and testing for specified microorganisms (e.g., Escherichia coli). |
| Test Item | Specification |
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| Appearance | Green solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
| Melting Point | 100–103 °C |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.