China Factory Direct
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| CAS number | 72235-52-0 |
| Product name | 2,4-Difluorobenzylamine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Synthesis of pharmaceutical intermediates | Used to synthesize fluorinated drug molecules |
| Agrochemical Industry | Preparation of active pharmaceutical ingredients (APIs) | Introduces fluorine atoms to enhance biological activity |
| Materials Chemistry | Preparation of specialty functional materials | Acts as a modifying monomer in polymerization reactions |
| Dyes and Pigments | Synthesis of organic dye intermediates | Participates in coupling or condensation reactions |
| Fine Chemicals | Synthesis of specialty chemicals | Derivatization of fluorinated aromatic compounds |
| Test Item | Common Testing Method | Method Overview |
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| Purity Analysis | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column with methanol/water or acetonitrile/water as the mobile phase, and a UV detector (typically at 254 nm). Effectively separates 2,4-difluorobenzylamine from its impurities with accurate quantification; suitable for assay determination of the main component. |
| Impurity Analysis | Gas Chromatography (GC) | Suitable for detecting volatile impurities. Employs a capillary column (e.g., DB-5MS), programmed temperature ramping, and FID or MS detection. Sample derivatization (e.g., acetylation) may be required to enhance volatility and stability. |
| Structural Confirmation | Liquid Chromatography-Mass Spectrometry (LC-MS) | Combines liquid chromatographic separation with mass spectrometric identification, providing molecular weight information and characteristic fragment ions. Used for confirming compound structure, identifying isomers, and characterizing unknown impurities. Commonly applied in verification of new batches or impurity profiling in complex matrices. |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | ¹H NMR and ¹³C NMR provide detailed structural information, including substitution patterns and chemical environments. This is the gold standard method for confirming the structure of 2,4-difluorobenzylamine. |
| Assay Determination | Ultraviolet-Visible Spectrophotometry (UV-Vis) | Measures concentration based on absorbance at specific wavelengths (e.g., 254–270 nm) using a calibration curve. Simple to operate, but susceptible to interference from co-existing impurities; suitable for preliminary screening. |
| Residual Solvent Analysis | Gas Chromatography-Mass Spectrometry (GC-MS) | Detects organic solvents possibly remaining from synthesis (e.g., ethanol, acetone, dichloromethane). Uses headspace or direct injection combined with mass spectrometry for qualitative and quantitative analysis, compliant with ICH Q3A/Q3C guidelines. |
| Moisture Content | Karl Fischer Titration (KF) | A specific method for water determination, offering high sensitivity and accuracy. Suitable for precise measurement of trace moisture in solid or liquid samples; recommended by pharmacopoeias. |
| Melting Point Determination | Micro Melting Point Apparatus | Determines sample identity and purity by observing the temperature range over which it melts. The typical melting point of 2,4-difluorobenzylamine is approximately 60–64 °C, useful for preliminary quality assessment. |
| Test Item | Specification |
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| Appearance | Colorless to pale yellow liquid |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Refractive Index (n20/D) | 1.512–1.516 |
| Relative Density (20°C/25°C) | 1.175–1.185 g/cm³ |
| Odor | Characteristic amine odor |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.